Corpora amylacea are associated with tau burden and cognitive status in Alzheimer's disease

CM Wander, THM Tsujimoto, JF Ervin, C Wang… - Acta Neuropathologica …, 2022 - Springer
Corpora amylacea (CA) and their murine analogs, periodic acid Schiff (PAS) granules, are
age-related, carbohydrate-rich structures that serve as waste repositories for aggregated …

[HTML][HTML] Corpora amylacea in neurodegenerative diseases: cause or effect?

TT Rohn - International journal of neurology and neurotherapy, 2015 - ncbi.nlm.nih.gov
The presence of corpora amylacea (CA) in the CNS is associated with both normal aging
and neurodegenerative conditions including Alzheimer's disease (AD) and vascular …

Lipopolysaccharide, Identified Using an Antibody and by PAS Staining, Is Associated With Corpora amylacea and White Matter Injury in Alzheimer's Disease and …

X Zhan, M Hakoupian, LW Jin… - Frontiers in Aging …, 2021 - frontiersin.org
Corpora amylacea (CA) increase in number and size with aging. Their origins and functions
remain unknown. Previously, we found that Alzheimer's disease (AD) brains have more CA …

Patterns of cortical and subcortical amyloid burden across stages of preclinical Alzheimer's disease

EC Edmonds, KJ Bangen, L Delano-Wood… - Journal of the …, 2016 - cambridge.org
Objectives: We examined florbetapir positron emission tomography (PET) amyloid scans
across stages of preclinical Alzheimer's disease (AD) in cortical, allocortical, and subcortical …

Exploring the elusive composition of corpora amylacea of human brain

E Augé, J Duran, JJ Guinovart, C Pelegrí, J Vilaplana - Scientific reports, 2018 - nature.com
Corpora amylacea (CA) are polyglucosan bodies that accumulate in the human brain during
ageing and are also present in large numbers in neurodegenerative conditions. Theories …

Neuropathological and sociodemographic factors associated with the cortical amyloid load in aging and Alzheimer's disease

SP da Silva, CCM de Castro, LN Rabelo… - Geroscience, 2024 - Springer
Alzheimer's disease (AD) is the leading cause of dementia and is characterized by a
progressive decline in cognitive abilities. A pathological hallmark of AD is a region-specific …

The amyloid pathology progresses in a neurotransmitter-specific manner

KFS Bell, A Ducatenzeiler, A Ribeiro-da-Silva… - Neurobiology of …, 2006 - Elsevier
Past studies using transgenic models of early-staged amyloid pathology, have suggested
that the amyloid pathology progresses in a neurotransmitter-specific manner where …

Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal sequence of amyloid-beta and tau …

ES Musiek, DM Holtzman - Current opinion in neurology, 2012 - journals.lww.com
Origins of Alzheimer's disease: reconciling cerebrospinal fl... : Current Opinion in Neurology
Origins of Alzheimer's disease: reconciling cerebrospinal fluid biomarker and …

Experimental induction of corpora amylacea in adult rat brain

HM Schipper - Microscopy research and technique, 1998 - Wiley Online Library
Corpora amylacea (CA) are glycoproteinaceous inclusions that accumulate in astroglia and
other brain cells as a function of advancing age and, to an even greater extent, in several …

Association of amyloid pathology with myelin alteration in preclinical Alzheimer disease

DC Dean, SA Hurley, SR Kecskemeti… - JAMA …, 2017 - jamanetwork.com
Importance The accumulation of aggregated β-amyloid and tau proteins into plaques and
tangles is a central feature of Alzheimer disease (AD). While plaque and tangle …