Subtyping of polyposis nasi: phenotypes, endotypes and comorbidities

M Koennecke, L Klimek, J Mullol, P Gevaert… - Allergo journal …, 2018 - Springer
Background Chronic rhinosinusitis (CRS) is a heterogeneous, multifactorial inflammatory
disease of the nasal and paranasal mucosa. It has not been possible to date to develop an …

Nasal polyposis pathophysiology: Endotype and phenotype open issues

G Brescia, C Zanotti, D Parrino, U Barion… - American Journal of …, 2018 - Elsevier
Purpose Endotyping chronic rhinosinusitis with nasal polyps (CRSwNP) poses a challenge
for rhinologists nowadays. Phenotyping CRSwNP proved inappropriate as an approach to …

A review of classification schemes for chronic rhinosinusitis with nasal polyposis endotypes

SK Dennis, K Lam, A Luong - Laryngoscope investigative …, 2016 - Wiley Online Library
Objective The recent development of endotypes to categorize disease variants of chronic
rhinosinusitis (CRS) reflects an evolving understanding of the various pathophysiologic and …

[HTML][HTML] Impact of allergy on phenotypic and endotypic profiles of nasal polyposis

G Mortuaire, I Gengler, M Balden, M Capron… - European Annals of …, 2018 - Elsevier
Objectives To assess the impact of allergy on clinical presentations (phenotypes) and
inflammatory patterns (endotypes) of chronic rhinosinusitis with nasal polyps (CRSwNP) …

Phenotypes in chronic rhinosinusitis

JP McCormick, HM Thompson, DY Cho… - Current allergy and …, 2020 - Springer
Abstract Purpose of Review Chronic rhinosinusitis (CRS) is a heterogenous disease
process affecting a significant proportion of the population and impacting quality of life and …

Inflammation and endotyping in chronic rhinosinusitis—a paradigm shift

S Ahern, A Cervin - Medicina, 2019 - mdpi.com
Chronic rhinosinusitis (CRS) is a heterogeneous chronic inflammatory condition of the
paranasal sinuses and nasal passage. It is characterized as inflammation of the sinonasal …

Chronic rhinosinusitis—could phenotyping or endotyping aid therapy?

N Bayar Muluk, C Cingi, GK Scadding… - American Journal of …, 2019 - journals.sagepub.com
Objectives We reviewed the phenotyping and endotyping of chronic rhinosinusitis (CRS)
and treatment options. Methods We searched PubMed, Google, Google Scholar, and the …

Chronic rhinosinusitis with nasal polyps

WW Stevens, RP Schleimer, RC Kern - The journal of allergy and clinical …, 2016 - Elsevier
Chronic rhinosinusitis with nasal polyps (CRSwNP) is an important clinical entity diagnosed
by the presence of both subjective and objective evidence of chronic sinonasal …

Immunopathogenesis of chronic rhinosinusitis and nasal polyposis

RP Schleimer - Annual Review of Pathology: Mechanisms of …, 2017 - annualreviews.org
Chronic rhinosinusitis (CRS) is a troublesome, chronic inflammatory disease that affects
over 10% of the adult population, causing decreased quality of life, lost productivity, and lost …

Endotypes of chronic rhinosinusitis with nasal polyps: pathology and possible therapeutic implications

C Bachert, B Marple, W Hosemann, C Cavaliere… - The Journal of Allergy …, 2020 - Elsevier
Today, chronic rhinosinusitis (CRS) is a symptomatic disease diagnosed by nasal
endoscopy and eventually computed tomography scan, and is treated by pharmacotherapy …