Novel pyridinium-type fullerene derivatives as multitargeting inhibitors of HIV-1 reverse transcriptase, HIV-1 protease, and HCV NS5B polymerase
T Kobayashi, T Yasuno, K Takahashi… - Bioorganic & Medicinal …, 2021 - Elsevier
In the present study, we newly synthesized four types of novel fullerene derivatives:
pyridinium/ethyl ester-type derivatives 3b− 3l, pyridinium/carboxylic acid-type derivatives 4a …
pyridinium/ethyl ester-type derivatives 3b− 3l, pyridinium/carboxylic acid-type derivatives 4a …
Fullerene derivatives as dual inhibitors of HIV-1 reverse transcriptase and protease
T Yasuno, T Ohe, H Kataoka, K Hashimoto… - Bioorganic & Medicinal …, 2021 - Elsevier
In the present study, we newly synthesized three types of novel fullerene derivatives:
pyridinium-type derivatives trans-3a and 4a-5b, piperidinium-type derivative 9, and proline …
pyridinium-type derivatives trans-3a and 4a-5b, piperidinium-type derivative 9, and proline …
The human immunodeficiency virus-reverse transcriptase inhibition activity of novel pyridine/pyridinium-type fullerene derivatives
T Yasuno, T Ohe, K Takahashi, S Nakamura… - Bioorganic & Medicinal …, 2015 - Elsevier
In the present study, we describe the synthesis of a novel set of pyridine/pyridinium-type
fullerene derivatives. The products were assessed for human immunodeficiency virus …
fullerene derivatives. The products were assessed for human immunodeficiency virus …
Human immunodeficiency virus-reverse transcriptase inhibition and hepatitis C virus RNA-dependent RNA polymerase inhibition activities of fullerene derivatives
T Mashino, K Shimotohno, N Ikegami… - Bioorganic & medicinal …, 2005 - Elsevier
We examined the human immunodeficiency virus-reverse transcriptase and hepatitis C virus
RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid …
RNA-dependent RNA polymerase inhibition activities of cationic, anionic, and amino acid …
Synthesis of novel amino acid-type fullerenes and their inhibition activity of HIV reverse transcriptase and HCV RNA polymerase
中村, 成夫, 下遠野, 高橋 - 共立薬科大学雑誌, 2006 - cir.nii.ac.jp
We synthesized novel fullerene derivatives with amino, carboxylic, and ethyl ester groups.
The HIV reverse transcriptase (HIV-RT) inhibition activities of these derivatives were higher …
The HIV reverse transcriptase (HIV-RT) inhibition activities of these derivatives were higher …
Development of Bio-Active Fullerene Derivatives Suitable for Drug
T Mashino - Yakugaku Zasshi: Journal of the Pharmaceutical …, 2022 - europepmc.org
Fullerene (C 60) and fullerene derivatives are attractive novel compounds not only for
carbon materials of nanotechnology but also for medical fields because of its unique …
carbon materials of nanotechnology but also for medical fields because of its unique …
Fullerene Derivatives of Nucleoside HIV Reverse Transcriptase Inhibitors—In Silico Activity Prediction
A Dąbrowska, T Pieńko, P Taciak, K Wiktorska… - International Journal of …, 2018 - mdpi.com
Here we present new derivatives of nucleoside reverse transcriptase inhibitors with a C20
fullerene. The computational chemistry methods used in this study evaluate affinity of …
fullerene. The computational chemistry methods used in this study evaluate affinity of …
Structural and electronic properties of new fullerene derivatives and their possible application as HIV-1 protease inhibitors
Density functional theory (DFT) calculations have been carried out at the hybrid Becke 3-Lee–
Yang–Parr; B3LYP/3-21G** level of theory to study two series of hydroxy-chalca-acetic acid …
Yang–Parr; B3LYP/3-21G** level of theory to study two series of hydroxy-chalca-acetic acid …
Novel fullerene derivatives as dual inhibitors of Hepatitis C virus NS5B polymerase and NS3/4A protease
H Kataoka, T Ohe, K Takahashi, S Nakamura… - Bioorganic & medicinal …, 2016 - Elsevier
We evaluated the Hepatitis C virus (HCV) NS5B polymerase and HCV NS3/4A protease
inhibition activities of a new set of proline-type fullerene derivatives. All of the compounds …
inhibition activities of a new set of proline-type fullerene derivatives. All of the compounds …
Design and synthesis of novel [60] fullerene derivatives as potential HIV aspartic protease inhibitors
GL Marcorin, T Da Ros, S Castellano… - Organic …, 2000 - ACS Publications
Design and Synthesis of Novel [60]Fullerene Derivatives as Potential HIV Aspartic Protease
Inhibitors | Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In …
Inhibitors | Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In …
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