▪ Abstract Exocytosis is fundamental in biology and requires an orchestra of proteins and
other constituents to fuse a vesicle with the plasma membrane. Although the molecular …

Pulmonary surfactant, secreted via exocytosis of lamellar bodies (LB) by alveolar type II (AT
II) cells, maintains low alveolar surface tension and is therefore essential for normal lung …

Molecular mechanisms of surfactant delivery to the air/liquid interface in the lung, which is
crucial to lower the surface tension, have been studied for more than two decades. Lung …

Type II pneumocytes secrete surfactant, a lipoprotein‐like substance reducing the surface
tension in the lung, by regulated exocytosis of secretory vesicles termed lamellar bodies …

Secretion of lung surfactant is the direct step in release of the lipoprotein-like product,
synthesized in lung epithelial type II cells, onto the alveolar surface. Release of surfactant …

Secretion of vesicular contents by exocytosis is a fundamental cellular process. Increasing
evidence suggests that post-fusion events play an important role in determining the …

The release of pulmonary surfactant by alveolar type II (ATII) cells is essential for lowering
surface tension at the respiratory air‐liquid interface, stabilizing the lungs against physical …

The molecular basis involving adsorption of pulmonary surfactant at the respiratory air–
liquid interface and the specific roles of the surfactant proteins SP-B and SP-C in this …

We simulated spontaneous fusion of small unilamellar vesicles mediated by lung surfactant
protein B (SP-B) using the MARTINI force field. An SP-B monomer triggers fusion events by …

Pulmonary surfactant (PS) is an essential complex of lipids and specific proteins synthesized
in alveolar type II pneumocytes, where it is assembled and stored intracellularly as …