Host immunity and HBV S gene mutation in HBsAg-negative HBV-infected patients
X Liu, S Chen, H Liu, J Lou - Frontiers in Immunology, 2023 - frontiersin.org
Background Clinically, some patients whose HBsAg becomes negative owing to antiviral
therapy or spontaneously still show a low level of HBV DNA persistence in serum. T …
therapy or spontaneously still show a low level of HBV DNA persistence in serum. T …
Effect of S-region mutations on HBsAg in HBsAg-negative HBV-infected patients
H Liu, S Chen, X Liu, J Lou - Virology Journal, 2024 - Springer
Abstract Background Occult HBV infection (OBI) is a special form of hepatitis B virus (HBV)
infection that may cause Liver cirrhosis and hepatocellular carcinoma, causing significant …
infection that may cause Liver cirrhosis and hepatocellular carcinoma, causing significant …
Sequence analysis of the HBV S protein in Chinese patients with coexisting HBsAg and anti‐HBs antibodies
F Ding, HG Yu, YX Li, N Cui, JF Dai… - Journal of Medical …, 2015 - Wiley Online Library
The coexistence of hepatitis B surface antigen (HBsAg) and antibodies to HBsAg (anti‐HBs)
in patients with hepatitis B virus (HBV) infection has been discovered and explained for …
in patients with hepatitis B virus (HBV) infection has been discovered and explained for …
Immune-Escape Mutations Are Prevalent among Patients with a Coexistence of HBsAg and Anti-HBs in a Tertiary Liver Center in the United States
The concurrent seropositivity of HBsAg and anti-HBs has been described among patients
with chronic hepatitis B (CHB), but its prevalence is variable. HBV S-gene mutations can …
with chronic hepatitis B (CHB), but its prevalence is variable. HBV S-gene mutations can …
Analysis of S gene characteristic sequences and changes in properties of protein expression in HBV ASCs with low-level HBsAg
Y Yu, Y Zhang, Y Dai, Q Sun, C Jiang, X Xu… - Frontiers in …, 2022 - frontiersin.org
Objective We detected the serum HBsAg immune complex (HBsAg-CIC) and sequenced the
HBV S gene in these patients to reveal the association between sustained low-level …
HBV S gene in these patients to reveal the association between sustained low-level …
Mutation in the S gene of hepatitis B virus and anti‐HBs subtype‐nonspecificity contributed to the co‐existence of HBsAg and anti‐HBs in patients with chronic …
X Fu, J Chen, H Chen, J Lin, Z Xun, S Li… - Journal of Medical …, 2017 - Wiley Online Library
The mechanism for the co‐existence of hepatitis B surface antigen (HBsAg) and antibodies
to HBsAg (anti‐HBs) in chronic HBV infected patients remains controversial. This study …
to HBsAg (anti‐HBs) in chronic HBV infected patients remains controversial. This study …
Analysis of clinical characteristics and S gene sequences in chronic asymptomatic HBV carriers with low-level HBsAg
T Wang, D Cui, S Chen, X Xu, C Sun, Y Dai… - Clinics and research in …, 2019 - Elsevier
Background During the natural hepatitis B virus (HBV) infection process, some infected
subjects are characterized by a sustained low serum HBV surface antigen (HBsAg) …
subjects are characterized by a sustained low serum HBV surface antigen (HBsAg) …
Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg …
R Salpini, A Battisti, L Piermatteo, L Carioti… - Emerging Microbes & …, 2020 - Taylor & Francis
Increasing evidences suggest that HBsAg-production varies across HBV-genotypes. HBsAg
C-terminus plays a crucial role for HBsAg-secretion. Here, we evaluate HBsAg-levels in …
C-terminus plays a crucial role for HBsAg-secretion. Here, we evaluate HBsAg-levels in …
[HTML][HTML] Sequence analysis of the Pre-S gene in chronic asymptomatic HBV carriers with low-level HBsAg
T Wang, Y Dai, M Zhang, D Cui… - International …, 2018 - spandidos-publications.com
In a hepatitis B virus (HBV)‑infected population, persistently low expression levels of serum
HBV serum antigen (HBsAg) are present, particularly in chronic asymptomatic HBV carriers …
HBV serum antigen (HBsAg) are present, particularly in chronic asymptomatic HBV carriers …
Immunocompromised Patients with HBsAg a Determinant Mutants: Comparison of HBsAg Diagnostic Assays
E Veropalumbo, A Marrone, L Vallefuoco, G Perruolo… - Intervirology, 2010 - karger.com
Hepatitis B surface antigen (HBsAg) is considered the best marker for the diagnosis of
hepatitis B virus (HBV) infection. Mutations of the s gene involving amino acid substitutions …
hepatitis B virus (HBV) infection. Mutations of the s gene involving amino acid substitutions …