[HTML][HTML] Pathogenesis of polycystic ovary syndrome: multifactorial assessment from the foetal stage to menopause

AS De Melo, SV Dias, R de Carvalho Cavalli… - …, 2015 - rep.bioscientifica.com
Polycystic ovary syndrome (PCOS) is a multifactorial disorder that arises from interactions
between genetic, environmental and intra-uterine factors. Small-for-gestational-age (SGA) …

Pathophysiology of polycystic ovary syndrome revisited: Current understanding and perspectives regarding future research

M Harada - Reproductive medicine and biology, 2022 - Wiley Online Library
Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder
among reproductive‐age women and has lifelong effects on health. Methods In this review, I …

The role of genetics, epigenetics and lifestyle in polycystic ovary syndrome development: the state of the art

V Bruni, A Capozzi, S Lello - Reproductive Sciences, 2022 - Springer
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disease affecting about 20–
25% of women in reproductive age. Different mechanisms could contribute to the …

Development of polycystic ovary syndrome: involvement of genetic and environmental factors

S Franks, MI McCarthy, K Hardy - International journal of …, 2006 - Wiley Online Library
We have recently proposed that polycystic ovary syndrome (PCOS) has its origin in fetal life.
This hypothesis is based on data from animal models (rhesus monkey or sheep that have …

The development of the polycystic ovary syndrome: family history as a risk factor

M Kahsar-Miller, R Azziz - Trends in Endocrinology & Metabolism, 1998 - cell.com
Three general genetic models for the development of the polycystic ovary syndrome (PCOS)
can be proposed, namely:(1) the" single-gene Mendelian" model, which considers the …

[HTML][HTML] Present status of understanding on the genetic etiology of polycystic ovary syndrome

S Dasgupta, MB Reddy - Journal of postgraduate medicine, 2008 - journals.lww.com
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of
reproductive age with a prevalence of approximately 7-10% worldwide. PCOS reflects …

[HTML][HTML] Ovarian and extra-ovarian mediators in the development of polycystic ovary syndrome

M Puttabyatappa… - Journal of molecular …, 2018 - jme.bioscientifica.com
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder affecting women
of reproductive age. The origin of PCOS is still not clear and appears to be a function of …

Genetics of polycystic ovary syndrome

CK Welt, JM Duran - Seminars in reproductive medicine, 2014 - thieme-connect.com
The etiology of polycystic ovary syndrome (PCOS) has been difficult to determine because
its features are heterogeneous, and its origin may also be heterogeneous. Twin studies …

Epigenetic inheritance of polycystic ovary syndrome—challenges and opportunities for treatment

E Stener-Victorin, Q Deng - Nature Reviews Endocrinology, 2021 - nature.com
Polycystic ovary syndrome (PCOS) is the main cause of female infertility worldwide and is
associated with a substantially increased lifetime risk of comorbidities, including type 2 …

[HTML][HTML] The prevalence of polycystic ovary syndrome: a brief systematic review

R Deswal, V Narwal, A Dang… - Journal of human …, 2020 - journals.lww.com
Background: Polycystic ovary syndrome (PCOS), the major endocrinopathy among
reproductive-aged women, is not yet perceived as an important health problem in the world …