Wnt/β-catenin signaling has been broadly implicated in human cancers and experimental
cancer models of animals. Aberrant activation of Wnt/β-catenin signaling is tightly linked with …

Wnt proteins are a large family of secreted glycoproteins. Wnt proteins bind to the Frizzled
receptors and LRP5/6 co-receptors, and through stabilizing the critical mediator β-catenin …

The aberrant Wnt/β-catenin signaling pathway facilitates cancer stem cell renewal, cell
proliferation and differentiation, thus exerting crucial roles in tumorigenesis and therapy …

The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in
embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin …

WNT/β-catenin signaling orchestrates various physiological processes, including embryonic
development, growth, tissue homeostasis, and regeneration. Abnormal WNT/β-catenin …

The WNT pathway is a pleiotropic signaling pathway that controls developmental processes,
tissue homeostasis, and cancer. The WNT pathway is commonly mutated in many cancers …

Introduction: The Wnt/β-catenin signaling pathway plays a pivotal role in the regulation of
cell growth, cell development and the differentiation of normal stem cells. Constitutive …

Wnt/β-catenin signaling is implicated in many physiological processes, including
development, tissue homeostasis, and tissue regeneration. In human cancers, Wnt/β-catenin …

Several signaling pathways have been identified as important for developmental processes.
One of such important cascades is the Wnt/β‐catenin signaling pathway, which can regulate …

The Wnt/β-catenin signaling pathway is tightly regulated and has important functions in
development, tissue homeostasis, and regeneration. Deregulation of Wnt/β-catenin …