Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular …

R Rosso, JM Kalman, O Rogowski, S Diamant, A Birger… - Heart Rhythm, 2007 - Elsevier
BACKGROUND: The mainstay of therapy for catecholaminergic polymorphic ventricular
tachycardia (CPVT) is maximal doses of β-blockers. However, although β-blockers prevent …

[HTML][HTML] Nadolol decreases the incidence and severity of ventricular arrhythmias during exercise stress testing compared with β1-selective β-blockers in patients with …

IS Leren, J Saberniak, E Majid, TF Haland… - Heart Rhythm, 2016 - Elsevier
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an
inheritable cardiac disease predisposing to malignant ventricular arrhythmias. Objective We …

Catecholaminergic polymorphic ventricular tachycardia

N Liu, Y Ruan, SG Priori - Progress in cardiovascular diseases, 2008 - Elsevier
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a highly malignant form of
arrhythmogenic disorder characterized by exercise-or emotional-induced polymorphic …

Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients

M Faggioni, HS Hwang, C van der Werf… - Circulation …, 2013 - Am Heart Assoc
Rationale: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by
mutations in cardiac ryanodine receptor (RyR2) or calsequestrin (Casq2) genes. Sinoatrial …

High prevalence of exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia mutation-positive family members diagnosed by cascade …

KH Haugaa, IS Leren, KE Berge, J Bathen… - Europace, 2010 - academic.oup.com
Aim Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac
disease predisposing to life-threatening arrhythmias. We aimed to determine the prevalence …

Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia

C van der Werf, PJ Kannankeril, F Sacher… - Journal of the American …, 2011 - jacc.org
Objectives: This study evaluated the efficacy and safety of flecainide in addition to
conventional drug therapy in patients with catecholaminergic polymorphic ventricular …

Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular …

H Watanabe, C van der Werf, F Roses-Noguer, A Adler… - Heart rhythm, 2013 - Elsevier
BACKGROUND: Conventional therapy with beta-blockers is incompletely effective in
preventing arrhythmic events in patients with catecholaminergic polymorphic ventricular …

Familial polymorphic ventricular arrhythmias: a quarter century of successful medical treatment based on serial exercise-pharmacologic testing

JD Fisher, D Krikler, KA Hallidie-Smith - Journal of the American College of …, 1999 - jacc.org
OBJECTIVES We sought to determine whether objective tests of antiarrhythmic drug efficacy
could produce favorable short-and long-term outcomes in a family with idiopathic malignant …

Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments

C van der Werf, AH Zwinderman, AAM Wilde - Europace, 2012 - academic.oup.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia
syndrome characterized by bidirectional or polymorphic ventricular arrhythmias under …

Efficacy of flecainide in the treatment of catecholaminergic polymorphic ventricular tachycardia: a randomized clinical trial

PJ Kannankeril, JP Moore, M Cerrone, SG Priori… - JAMA …, 2017 - jamanetwork.com
Importance Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially
lethal genetic arrhythmia syndrome characterized by polymorphic ventricular tachycardia …