Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

Renal stone disease is a frequent condition, causing a huge burden on health care systems
globally. Calcium-based calculi account for around 75% of renal stone disease and the …

Nephrolithiasis is a prevalent condition with a high morbidity. Although dozens of
monogenic causes have been identified, the fraction of single-gene disease has not been …

Kidney stone disease (nephrolithiasis) is a common problem that can be associated with
alterations in urinary solute composition including hypercalciuria. Studies suggest that the …

With a lifetime incidence of up to 12% in man and 6% in woman, nephrolithiasis is a major
health problem worldwide. Approximately, 80% of kidney stones are composed of calcium …

Urolithiasis affects approximately 10% of individuals in Western societies by the seventh
decade of life. The most common form, idiopathic calcium oxalate urolithiasis, results from …

The formation of stones in the urinary tract stems from a wide range of underlying disorders.
That clinicians look for the underlying causes for nephrolithiasis is imperative to direct …

Nephrolithiasis, with a lifetime incidence of up to 13%(1–9), results in significant morbidity as
well as substantial economic costs, not only directly from medical treatment but also …

Calcium nephrolithiasis is one of the most prevalent uronephrologic disorders in the western
countries. Studies in families and twins evidenced a genetic predisposition to calcium …

Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden with a
heritability of~ 45–60%. We present genome-wide association studies in British and …