RNA polymerase II phosphorylation and gene looping: new roles for the Rpb4/7 heterodimer in regulating gene expression

O Calvo - Current Genetics, 2020 - Springer
In eukaryotes, cellular RNAs are produced by three nuclear RNA polymerases (RNAPI, II,
and III), which are multisubunit complexes. They share structural and functional features …

Crystal structure of RPB5, a universal eukaryotic RNA polymerase subunit and transcription factor interaction target

F Todone, ROJ Weinzierl, P Brick… - Proceedings of the …, 2000 - National Acad Sciences
Eukaryotic nuclei contain three different types of RNA polymerases (RNAPs), each
consisting of 12–18 different subunits. The evolutionarily highly conserved RNAP subunit …

Rpb4 and Rpb7: subunits of RNA polymerase II and beyond

M Choder - Trends in biochemical sciences, 2004 - cell.com
RNA Polymerase II (pol II) is a large multi-subunit complex that is responsible for the
synthesis of all eukaryotic mRNAs. Its correct and timely recruitment to promoter regions is a …

Gpn2 and Rba50 directly participate in the assembly of the Rpb3 subcomplex in the biogenesis of RNA polymerase II

F Zeng, Y Hua, X Liu, S Liu, K Lao… - Molecular and cellular …, 2018 - Taylor & Francis
ABSTRACT RNA polymerase II (RNAPII) is one of the central enzymes in cell growth and
organizational development. It is a large macromolecular complex consisting of 12 subunits …

Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation

P Allepuz-Fuster, V Martínez-Fernández… - Nucleic acids …, 2014 - academic.oup.com
Abstract The Rpb4 and Rpb7 subunits of eukaryotic RNA polymerase II (RNAPII) participate
in a variety of processes from transcription, DNA repair, mRNA export and decay, to …

Quantitative proteomics demonstrates that the RNA polymerase II subunits Rpb4 and Rpb7 dissociate during transcriptional elongation

AL Mosley, GO Hunter, ME Sardiu, M Smolle… - Molecular & Cellular …, 2013 - ASBMB
Eukaryotic RNA polymerase II (RNAPII) is a 12-subunit enzyme that is responsible for the
transcription of messenger RNA. Two of the subunits of RNA polymerase II, Rpb4 and Rpb7 …

The C-terminal domain of Rpb1 functions on other RNA polymerase II subunits

H Suh, DZ Hazelbaker, LM Soares, S Buratowski - Molecular cell, 2013 - cell.com
The C-terminal domain (CTD) of Rpb1, the largest subunit of RNA polymerase II (RNApII),
coordinates recruitment of RNA-and chromatin-modifying factors to transcription complexes …

Distinct regions of RPB11 are required for heterodimerization with RPB3 in human and yeast RNA polymerase II

WJ Benga, S Grandemange… - Nucleic acids …, 2005 - academic.oup.com
In Saccharomyces cerevisiae, RNA polymerase II assembly is probably initiated by the
formation of the RPB3–RPB11 heterodimer. RPB3 is encoded by a single copy gene in the …

New insights into the biogenesis of nuclear RNA polymerases?

P Cloutier, B Coulombe - Biochemistry and Cell Biology, 2010 - cdnsciencepub.com
More than 30 years of research on nuclear RNA polymerases (RNAP I, II, and III) has
uncovered numerous factors that regulate the activity of these enzymes during the …

Rpb4 and Rpb7: multifunctional subunits of RNA polymerase II

N Sharma, R Kumari - Critical reviews in microbiology, 2013 - Taylor & Francis
The 12-subunit RNA polymerase II enzyme in yeasts and higher eukaryotic cells is important
for transcription of protein-coding genes. Its fourth and seventh largest subunits named …