Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: the NEURAPRO randomized clinical trial

PD McGorry, B Nelson, C Markulev, HP Yuen… - JAMA …, 2017 - jamanetwork.com
Importance A promising treatment to prevent onset and improve outcomes in patients at
ultrahigh risk for psychosis is dietary supplementation with long-chain ω-3 polyunsaturated …

Long-chain ω-3 fatty acids for indicated prevention of psychotic disorders: a randomized, placebo-controlled trial

GP Amminger, MR Schäfer… - Archives of general …, 2010 - jamanetwork.com
Context The use of antipsychotic medication for the prevention of psychotic disorders is
controversial. Long-chain ω-3 (omega-3) polyunsaturated fatty acids (PUFAs) may be …

[HTML][HTML] Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study

GP Amminger, MR Schäfer, M Schlögelhofer… - Nature …, 2015 - nature.com
Long-chain omega-3 polyunsaturated fatty acids (PUFAs) are essential for neural
development and function. As key components of brain tissue, omega-3 PUFAs play critical …

The NEURAPRO biomarker analysis: long-chain omega-3 fatty acids improve 6-month and 12-month outcomes in youths at ultra-high risk for psychosis

GP Amminger, B Nelson, C Markulev, HP Yuen… - Biological …, 2020 - Elsevier
Background NEURAPRO was a multicenter, placebo-controlled trial of long-chain omega-3
polyunsaturated fatty acids (n-3 PUFAs)(fish oil) in 304 individuals at ultra-high risk for …

Omega-3 fatty acid supplementation in adolescents with borderline personality disorder and ultra-high risk criteria for psychosis: a post hoc subgroup analysis of a …

GP Amminger, AM Chanen, S Ohmann… - The Canadian …, 2013 - journals.sagepub.com
Objective: To investigate whether long-chain omega-3 (n-3) polyunsaturated fatty acids
(PUFAs) improve functioning and psychiatric symptoms in young people with borderline …

Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid?

BM Ross, J Seguin, LE Sieswerda - Lipids in health and disease, 2007 - Springer
Background A growing number of observational and epidemiological studies have
suggested that mental illness, in particular mood disorders, is associated with reduced …

A potential role for adjunctive omega-3 polyunsaturated fatty acids for depression and anxiety symptoms in recent onset psychosis: Results from a 16 week …

DG Robinson, JA Gallego, M John, LA Hanna… - Schizophrenia …, 2019 - Elsevier
Omega-3 treatment studies for multi-episode schizophrenia or clinical high risk for
conversion to psychosis states have had variable, and often negative, results. To examine …

Beneficial effects of omega-3 fatty acid supplementation in schizophrenia: possible mechanisms

MC Hsu, YS Huang, WC Ouyang - Lipids in health and disease, 2020 - Springer
Background Schizophrenia is a serious long-term psychotic disorder marked by positive and
negative symptoms, severe behavioral problems and cognitive function deficits. The cause …

[HTML][HTML] Unsaturated fatty acids in mental disorders: An umbrella review of meta‐analyses

X Gao, X Su, X Han, H Wen, C Cheng, S Zhang, W Li… - Advances in …, 2022 - Elsevier
Unsaturated fatty acids might be involved in the prevention of and improvement in mental
disorders, but the evidence on these associations has not been comprehensively assessed …

Randomized-controlled trials in people at ultra high risk of psychosis: a review of treatment effectiveness

A Preti, M Cella - Schizophrenia research, 2010 - Elsevier
As an extension of the early intervention in psychosis paradigm, different focused treatments
are now offered to individuals at ultra high risk of psychosis (UHR) to prevent transition to …