Among the transition metals, copper-based catalyst systems enable the widest range of N-
containing reagents in C–H amination to allow for the direct incorporation of versatile N …

Transition metal-catalyzed C–H amination at positions adjacent to double bonds and
carbonyl groups is discussed in this critical review. While the focus will center on the recent …

Catalytic CÀH amination is an attractive strategy to prepare CÀN bonds without the need for
a pre-functionalized site.[1–3] This approach offers substantial opportunities to streamline …

Catalytic transformation of ubiquitous C–H bonds into valuable C–N bonds offers an efficient
synthetic approach to construct N-functionalized molecules. Over the last few decades …

Nitrogen-containing compounds are the most common structural architectures in drug
candidates, natural and biological products, and small-molecule therapeutics. Within the …

Nitrogen heterocycles are of great medicinal importance, and the construction of nitrogen
heterocyclic scaffolds has been one of the focuses in synthetic organic chemistry. Recently …

A dinuclear Co (II) complex supported by a modular, tunable redox-active ligand system is
capable of selective C–H amination to form indolines from aryl azides in good yields at low …

Conspectus Owing to the prevalence of nitrogen-containing compounds in functional
materials, natural products and important pharmaceutical agents, chemists have actively …

The direct amination of C–H bonds with ammonia is a challenge in synthetic chemistry.
Herein, we present a copper-mediated approach that enables a chelation-assisted aromatic …

Catalytic C–H amination has recently emerged as a unique tool for the synthesis of amines.
This tutorial review highlights the existing protocols catalyzed by metal complexes (rhodium …