Efficacy and safety of intravenous mesenchymal stem cells for ischemic stroke

JW Chung, WH Chang, OY Bang, GJ Moon, SJ Kim… - Neurology, 2021 - AAN Enterprises
Objective To test whether autologous modified mesenchymal stem cells (MSCs) improve
recovery in patients with chronic major stroke. Methods In this prospective, open-label …

From the lab to patients: a systematic review and meta-analysis of mesenchymal stem cell therapy for stroke

MM Lalu, J Montroy, D Dowlatshahi, B Hutton… - Translational stroke …, 2020 - Springer
There may be the potential to improve stroke recovery with mesenchymal stem cells (MSCs);
however, questions about the efficacy and safety of this treatment remain. To address these …

Autologous mesenchymal stem cells in chronic stroke

A Bhasin, MVP Srivastava, SS Kumaran… - Cerebrovascular …, 2011 - karger.com
Background: Cell transplantation is a 'hype and hope'in the current scenario. It is in the early
stage of development with promises to restore function in chronic diseases. Mesenchymal …

Autologous mesenchymal stem cells improve motor recovery in subacute ischemic stroke: a randomized clinical trial

A Jaillard, M Hommel, A Moisan, TA Zeffiro… - Translational stroke …, 2020 - Springer
While preclinical stroke studies have shown that mesenchymal stem cells (MSCs) promote
recovery, few randomized controlled trials (RCT) have assessed cell therapy in humans. In …

Autologous mesenchymal stem cell transplantation in stroke patients

OY Bang, JS Lee, PH Lee, G Lee - Annals of Neurology: Official …, 2005 - Wiley Online Library
Mesenchymal stem cell (MSC) transplantation improves recovery from ischemic stroke in
animals. We examined the feasibility, efficacy, and safety of cell therapy using culture …

Mesenchymal stem cell therapy in stroke: a systematic review of literature in pre-clinical and clinical research

H Zheng, B Zhang, PY Chhatbar, Y Dong… - Cell …, 2018 - journals.sagepub.com
Exogenous stem cell therapy (SCT) has been recognized recently as a promising
neuroregenerative strategy to augment recovery in stroke survivors. Mesenchymal stem …

Efficacy of intravenous mesenchymal stem cells for motor recovery after ischemic stroke: a neuroimaging study

J Lee, WH Chang, JW Chung, SJ Kim, SK Kim, JS Lee… - Stroke, 2022 - Am Heart Assoc
Background and Purpose: Stem cell–based therapy is a promising approach to repair brain
damage after stroke. This study was conducted to investigate changes in neuroimaging …

[HTML][HTML] Phase I/II study of safety and preliminary efficacy of intravenous allogeneic mesenchymal stem cells in chronic stroke

ML Levy, JR Crawford, N Dib, L Verkh, N Tankovich… - Stroke, 2019 - journals.lww.com
Background and Purpose—Stroke is a leading cause of long-term disability. Limited
treatment options exist for patients with chronic stroke and substantial functional deficits. The …

A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke

JS Lee, JM Hong, GJ Moon, PH Lee, YH Ahn… - Stem …, 2010 - academic.oup.com
We previously evaluated the short-term follow-up preliminary data of mesenchymal stem
cells (MSCs) transplantation in patients with ischemic stroke. The present study was …

Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke

P Dharmasaroja - Journal of Clinical Neuroscience, 2009 - Elsevier
Bone marrow-derived mesenchymal stem cells (MSCs) have great potential as therapeutic
agents in stroke management, since they are easily accessible and can be rapidly …