The role of molecular pathological epidemiology in the study of neoplastic and non-neoplastic diseases in the era of precision medicine

S Ogino, R Nishihara, TJ VanderWeele, M Wang… - …, 2016 - journals.lww.com
Molecular pathology diagnostics to subclassify diseases based on pathogenesis are
increasingly common in clinical translational medicine. Molecular pathological epidemiology …

Integration of molecular pathology, epidemiology and social science for global precision medicine

A Nishi, DA Milner Jr, EL Giovannucci… - Expert review of …, 2016 - Taylor & Francis
The precision medicine concept and the unique disease principle imply that each patient
has unique pathogenic processes resulting from heterogeneous cellular genetic and …

[HTML][HTML] Molecular pathological epidemiology: new developing frontiers of big data science to study etiologies and pathogenesis

T Hamada, NN Keum, R Nishihara, S Ogino - Journal of gastroenterology, 2017 - Springer
Molecular pathological epidemiology (MPE) is an integrative field that utilizes molecular
pathology to incorporate interpersonal heterogeneity of a disease process into …

Interdisciplinary education to integrate pathology and epidemiology: towards molecular and population-level health science

S Ogino, EE King, AH Beck, ME Sherman… - American journal of …, 2012 - academic.oup.com
In recent decades, epidemiology, public health, and medical sciences have been
increasingly compartmentalized into narrower disciplines. The authors recognize the value …

Insights into pathogenic interactions among environment, host, and tumor at the crossroads of molecular pathology and epidemiology

S Ogino, JA Nowak, T Hamada… - Annual Review of …, 2019 - annualreviews.org
Evidence indicates that diet, nutrition, lifestyle, the environment, the microbiome, and other
exogenous factors have pathogenic roles and also influence the genome, epigenome …

Integration of microbiology, molecular pathology, and epidemiology: a new paradigm to explore the pathogenesis of microbiome‐driven neoplasms

T Hamada, JA Nowak, DA Milner Jr… - The Journal of …, 2019 - Wiley Online Library
Molecular pathological epidemiology (MPE) is an integrative transdisciplinary field that
addresses heterogeneous effects of exogenous and endogenous factors (collectively …

[HTML][HTML] Integrating precision cancer medicine into healthcare—policy, practice, and research challenges

G Bertier, J Carrot-Zhang, V Ragoussis, Y Joly - Genome medicine, 2016 - Springer
Precision medicine (PM) can be defined as a predictive, preventive, personalized, and
participatory healthcare service delivery model. Recent developments in molecular biology …

Molecular epidemiology and biomarkers in etiologic cancer research: the new in light of the old

P Vineis, F Perera - Cancer Epidemiology Biomarkers & Prevention, 2007 - AACR
The purpose of this review is to evaluate progress in molecular epidemiology over the past
24 years in cancer etiology and prevention to draw lessons for future research incorporating …

The evolving discipline of molecular epidemiology of cancer

MR Spitz, ML Bondy - Carcinogenesis, 2010 - academic.oup.com
Classical epidemiologic studies have made seminal contributions to identifying the etiology
of most common cancers. Molecular epidemiology was conceived of as an extension of …

Transforming epidemiology for 21st century medicine and public health

MJ Khoury, TK Lam, JPA Ioannidis, P Hartge… - … , biomarkers & prevention, 2013 - AACR
Abstract In 2012, the National Cancer Institute (NCI) engaged the scientific community to
provide a vision for cancer epidemiology in the 21st century. Eight overarching thematic …