Subtypes of functional α1-and α2-adrenoceptors

JR Docherty - European journal of pharmacology, 1998 - Elsevier
In this review, subtypes of functional α1-and α2-adrenoceptors are discussed. These are cell
membrane receptors, belonging to the seven transmembrane spanning G-protein-linked …

Subtypes of functional α1-adrenoceptor

JR Docherty - Cellular and molecular life sciences, 2010 - Springer
In this review, subtypes of functional α1-adrenoceptor are discussed. These are cell
membrane receptors, belonging to the seven-transmembrane-spanning G-protein-linked …

α2-Adrenoceptors: more subtypes but fewer functional differences

AC MacKinnon, M Spedding, CM Brown - Trends in pharmacological …, 1994 - cell.com
The proliferation of receptor subtypes based on differences in amino acid sequence does
not necessurily coincide with fun~ fiona~ differences. Tlze~~~~ er of-~~-adrenoce~ tor s …

The pharmacology of α1-adrenoceptor subtypes

JR Docherty - European journal of pharmacology, 2019 - Elsevier
This review examines the functions of α 1-adrenoceptor subtypes, particularly in terms of
contraction of smooth muscle. There are 3 subtypes of α 1-adrenoceptor, α 1A-α 1B-and α …

Pharmacologic characterization of cloned α1-adrenoceptor subtypes: selective antagonists suggest the existence of a fourth subtype

DA Schwinn, JW Lomasney - European Journal of Pharmacology …, 1992 - Elsevier
In membranes prepared from Cos-7 or HeLa cells expressing one of three individual cloned
α 1-adrenoceptor subtypes, competition with 2-{(β-(4-hydroxy-3-[125 I] iodophenyl) …

α1-Adrenoceptor subtypes

H Zhong, KP Minneman - European journal of pharmacology, 1999 - Elsevier
α1-Adrenoceptors are one of three subfamilies of receptors (α1, α2, β) mediating responses
to adrenaline and noradrenaline. Three α1-adrenoceptor subtypes are known (α1A, α1B …

Are the pharmacology and physiology of α2adrenoceptors determined by α2‐heteroreceptors and autoreceptors respectively?

R Gilsbach, L Hein - British journal of pharmacology, 2012 - Wiley Online Library
α2‐Adrenoceptors are important mediators of physiological responses to the endogenous
catecholamines noradrenaline and adrenaline. In addition, α2‐adrenoceptors are …

Updates in the function and regulation of α1‐adrenoceptors

J Akinaga, JA García‐Sáinz… - British journal of …, 2019 - Wiley Online Library
α1‐Adrenoceptors are seven transmembrane domain GPCRs involved in numerous
physiological functions controlled by the endogenous catecholamines, noradrenaline and …

Alpha-adrenoceptor subtypes

BC Calzada, AA de Artiñano - Pharmacological research, 2001 - Elsevier
Different studies have led to our present knowledge of the membrane receptors responsible
for mediating the responses to the endogenous catecholamines. These receptors were …

Classification of α1-adrenoceptor subtypes

MC Michel, B Kenny, DA Schwinn - Naunyn-Schmiedeberg's archives of …, 1995 - Springer
Two α 1-adrenoceptor subtypes (α 1A and α 1B) have been detected in various tissues by
pharmacological techniques, and three distinct cDNAs encoding α 1-adrenoceptor subtypes …