Engineering mesenchymal stem cells for regenerative medicine and drug delivery
Researchers have applied mesenchymal stem cells (MSC) to a variety of therapeutic
scenarios by harnessing their multipotent, regenerative, and immunosuppressive properties …
scenarios by harnessing their multipotent, regenerative, and immunosuppressive properties …
Optimizing mesenchymal stem cell-based therapeutics
Mesenchymal stem cell (MSC)-based therapeutics are showing significant benefit in multiple
clinical trials conducted by both academic and commercial organizations, but obstacles …
clinical trials conducted by both academic and commercial organizations, but obstacles …
Mesenchymal stem cell functionalization for enhanced therapeutic applications
D Kouroupis, C Sanjurjo-Rodriguez… - … Engineering Part B …, 2019 - liebertpub.com
To date, the therapeutic efficacy of human mesenchymal stem cells (hMSCs) has been
investigated in various clinical trials with moderate or, in some cases, inconsistent results …
investigated in various clinical trials with moderate or, in some cases, inconsistent results …
Mesenchymal stem cell-based drug delivery strategy: from cells to biomimetic
HH Wu, Y Zhou, Y Tabata, JQ Gao - Journal of Controlled Release, 2019 - Elsevier
Owing to the diversity and ease of preparation of nanomaterials, the rational nanocarriers
with a rational design have become increasingly popular in medical researches. Although …
with a rational design have become increasingly popular in medical researches. Although …
Mesenchymal stem cells beyond regenerative medicine
R Shammaa, AEH El-Kadiry, J Abusarah… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem cells (MSCs) are competent suitors of cellular therapy due to their
therapeutic impact on tissue degeneration and immune-based pathologies. Additionally …
therapeutic impact on tissue degeneration and immune-based pathologies. Additionally …
MSCs: delivery routes and engraftment, cell‐targeting strategies, and immune modulation
Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and
in clinical trials for multiple disease states. The differentiation, trophic, and …
in clinical trials for multiple disease states. The differentiation, trophic, and …
Mesenchymal stem cell‐based therapy: a new paradigm in regenerative medicine
Introduction• Mesenchymal stem cells and its characteristics• Experimental/preclinical MSC‐
based studies–MSC transplantation–Genetically modified MSC‐based therapy–MSC‐based …
based studies–MSC transplantation–Genetically modified MSC‐based therapy–MSC‐based …
Mesenchymal stem cells: an emerging tool for cancer targeting and therapy
V Fritz, C Jorgensen - Current stem cell research & therapy, 2008 - ingentaconnect.com
Mesenchymal stem cells (MSCs) from post-natal bone marrow possess tremendous
potential for cell-mediated gene therapy in several disease processes, and recent reports …
potential for cell-mediated gene therapy in several disease processes, and recent reports …
Shattering barriers toward clinically meaningful MSC therapies
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
Characterization and therapeutic applications of mesenchymal stem cells for regenerative medicine
J Wang, Z Chen, M Sun, H Xu, Y Gao, J Liu, M Li - Tissue and cell, 2020 - Elsevier
Abstract Background Mesenchymal stem cells (MSCs) are multipotent, genomic stable, self-
renewable, and culturally expandable adult stem cells. MSCs facilitate tissue development …
renewable, and culturally expandable adult stem cells. MSCs facilitate tissue development …