Skeletal muscle represents the largest body-composition component in humans. In addition
to its primary function in the maintenance of upright posture and the production of …

The skeletal muscle extracellular matrix (ECM) plays an important role in muscle fiber force
transmission, maintenance, and repair. In both injured and diseased states, ECM adapts …

The extracellular matrix (ECM) is an interconnected macromolecular scaffold occupying the
space between cells. Amongst other functions, the ECM provides structural support to …

As the primary producer of extracellular matrix (ECM) proteins in skeletal muscle, fibroblasts
play an important role providing structural support to muscle. Skeletal muscle ECM is vital for …

The muscle extracellular matrix (ECM) forms a complex network of collagens, proteoglycans,
and other proteins that produce a favorable environment for muscle regeneration, protect the …

The extracellular matrix (ECM) of skeletal muscle is critical for force transmission and for the
passive elastic response of skeletal muscle. Structural, biochemical, cellular, and functional …

Multinuclear muscle fibers are the most voluminous cells in skeletal muscle and the primary
drivers of growth in response to loading. Outside the muscle fiber, however, is a diversity of …

Skeletal muscle requires a highly orchestrated coordination between multiple cell types and
their microenvironment to exert its function and to maintain its homeostasis and regenerative …

Extracellular matrix (ECM) is a kind of connective tissue in the cell microenvironment, which
is of great significance to tissue development. ECM in muscle fiber niche consists of three …

Skeletal muscle (SM) comprises around 40% of total body weight and is among the most
important plastic tissues, as it supports skeletal development, controls body temperature …