The protective effects of aloperine against ox-LDL-induced endothelial dysfunction and inflammation in HUVECs

W Li, Y Li, Y Zhao, L Ren - Artificial Cells, Nanomedicine, and …, 2020 - Taylor & Francis
Atherosclerosis is a potentially life-threatening cardiovascular disease characterized by
chronic endothelial inflammation and the formation of atherosclerotic lesions. Circulating ox …

6‐Shogaol Protects against Oxidized LDL‐Induced Endothelial Injruries by Inhibiting Oxidized LDL‐Evoked LOX‐1 Signaling

YK Wang, YJ Hong, YH Yao, XM Huang… - Evidence‐Based …, 2013 - Wiley Online Library
Endothelial dysfunction and oxLDL are believed to be early and critical events in
atherogenesis. 6‐Shogaol is the major bioactive compound present in Zingiber officinale …

Schisanhenol ameliorates oxLDL‐caused endothelial dysfunction by inhibiting LOX‐1 signaling

TH Chiu, CW Ku, TJ Ho, KL Tsai… - Environmental …, 2023 - Wiley Online Library
Atherosclerotic lesions play a critical role in leading cardiovascular diseases. Oxidized low‐
density lipoprotein (OxLDL) is a vital risk factor for atherosclerosis since it acts a crucial role …

Hyperoside inhibits the effects induced by oxidized low-density lipoprotein in vascular smooth muscle cells via oxLDL-LOX-1-ERK pathway

Z Zhang, D Zhang, B Du, Z Chen - Molecular and cellular biochemistry, 2017 - Springer
Hyperoside is a major active constituent in many medicinal plants traditionally used in
Chinese medicines for their anti-inflammatory, antioxidative, and vascular protective effects …

Ursolic Acid Attenuates Atherosclerosis in ApoE−/− Mice: Role of LOX-1 Mediated by ROS/NF-κB Pathway

Q Li, W Zhao, X Zeng, Z Hao - Molecules, 2018 - mdpi.com
Atherosclerosis, a chronic inflammatory disease, is a major contributor to cardiovascular
diseases. Ursolic acid (UA) is a phytonutrient with widely biological effects including anti …

Miltirone protects human EA. hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 …

L Zhang, H Zhang, X Li, B Jia, Y Yang, P Zhou, P Li… - Phytomedicine, 2016 - Elsevier
Background Oxidized low-density lipoprotein (ox-LDL) is an underlying cause of endothelial
dysfunction, which is an early event in the pathogenesis of atherosclerosis. In our previous …

Dihydrohomoplantagin and Homoplantaginin, Major Flavonoid Glycosides from Salvia plebeia R. Br. Inhibit oxLDL-Induced Endothelial Cell Injury and Restrict …

N Meng, K Chen, Y Wang, J Hou, W Chu, S Xie, F Yang… - Molecules, 2022 - mdpi.com
Oxidized low-density lipoprotein (oxLDL)-induced endothelium injury promotes the
development of atherosclerosis. It has been reported that homoplantaginin, a flavonoid …

Atractylenolide I restores HO-1 expression and inhibits Ox-LDL-induced VSMCs proliferation, migration and inflammatory responses in vitro

W Li, W Zhi, F Liu, Z He, X Wang, X Niu - Experimental cell research, 2017 - Elsevier
Pathogenesis of atherosclerosis is characterized by the proliferation and migration of
vascular smooth muscle cells (VSMCs) and inflammatory lesions. The aim of this study is to …

Allicin prevents oxidized low-density lipoprotein-induced endothelial cell injury by inhibiting apoptosis and oxidative stress pathway

X Chen, S Pang, J Lin, J Xia, Y Wang - BMC complementary and …, 2016 - Springer
Background Vascular endothelial apoptosis is significantly associated with atherosclerosis
and cardiovascular diseases, for which oxidized low-density lipoprotein (ox-LDL) is a major …

Regulation of phospholipid peroxidation signaling by a traditional Chinese medicine formula for coronary heart disease

X Ma, Q Wang, C Liu, J Liu, G Luo, L He, T Yuan… - Phytomedicine, 2023 - Elsevier
Background Phospholipid peroxidation signaling was recently revealed as a novel
pathological mechanism of coronary heart disease (CHD), and small molecules involved in …