Simple Summary Chronic Myelogenous Leukemia (CML) is a common blood cancer that
involves the uncontrolled growth of certain blood cells. Treating this disease effectively …

We present a label-free microfluidic chip for the segregation of circulating leukemia cells
(CLCs) from blood samples, with a focus on its clinical applications in Acute Myeloid …

Chronic myelogenous/myeloid leukemia (CML) is a type of cancer of bone marrow that
arises from hematopoietic stem cells and affects millions of people worldwide. Eighty-five …

We report a highly sensitive microfluidic assay to detect minimal residual disease (MRD) in
patients with acute myeloid leukemia (AML) that samples peripheral blood to search for …

For cancer patients, the enumeration of rare circulating tumor cells (CTCs) in peripheral
blood is a strong prognostic indicator of the severity of the cancer; for the general population …

Background: Despite therapeutic advances, AML remains a disease in which the majority of
patients relapse after attaining remission. The presence of bone marrow MRD is associated …

Liquid biopsy is an alternative to invasive bone marrow biopsy for leukemia detection and
management. However, no robust technology is available for enriching leukemic blast cells …

The emergence of enabling technologies for the analysis of circulating tumor cells has been
shedding new lights into cancer management in the recent years. However, majority of the …

Long-term management for leukemia is challenging due to the painful and invasive
procedure of bone marrow (BM) biopsy. At present, non-invasive liquid (blood) biopsy is not …

Primary cancers disseminate both single circulating tumor cells (CTCs) and CTC “clusters,”
the latter of which have been shown to demonstrate greater metastatic propensity and …