The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview
The lateral habenula (LH b) is an epithalamic region with a crucial role in the regulation of
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
midbrain monoaminergic systems. Over the past few years a renewed interest in the LH b …
Circuits and functions of the lateral habenula in health and in disease
H Hu, Y Cui, Y Yang - Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …
owing to new discoveries relating to its critical role in regulating negatively motivated …
Habenular connections with the dopaminergic and serotonergic system and their role in stress‐related psychiatric disorders
The habenula (Hb) is a phylogenetically old epithalamic structure differentiated into two
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …
nuclear complexes, the medial (MHb) and lateral habenula (LHb). After decades of search …
[HTML][HTML] Synaptic and cellular profile of neurons in the lateral habenula
The lateral habenula (LHb) is emerging as a crucial structure capable of conveying
rewarding and aversive information. Recent evidence indicates that a rapid increase in the …
rewarding and aversive information. Recent evidence indicates that a rapid increase in the …
The lateral habenula and the serotonergic system
The habenula (Hb) is an epithalamic structure differentiated into two nuclear complexes,
medial (MHb) and lateral habenula (LHb). After decades of relative neglect, interest in the …
medial (MHb) and lateral habenula (LHb). After decades of relative neglect, interest in the …
[HTML][HTML] Understanding the habenula: A major node in circuits regulating emotion and motivation
Over the last decade, the understanding of the habenula has rapidly advanced from being
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
an understudied brain area with the Latin name 'habena” meaning “little rein”, to being …
[HTML][HTML] Dysregulation of the lateral habenula in major depressive disorder
CA Browne, R Hammack, I Lucki - Frontiers in synaptic neuroscience, 2018 - frontiersin.org
Clinical and preclinical evidence implicates hyperexcitability of the lateral habenula (LHb) in
the development of psychiatric disorders including major depressive disorder (MDD). This …
the development of psychiatric disorders including major depressive disorder (MDD). This …
Habenula: crossroad between the basal ganglia and the limbic system
O Hikosaka, SR Sesack, L Lecourtier… - Journal of …, 2008 - Soc Neuroscience
There is a growing awareness that emotion, motivation, and reward values are important
determinants of our behavior. The habenula is uniquely positioned both anatomically and …
determinants of our behavior. The habenula is uniquely positioned both anatomically and …
[HTML][HTML] Lateral habenula in the pathophysiology of depression
Depression is a devastating disorder with a combination of diverse symptoms such as low
self-esteem, lack of motivation, anhedonia, loss of appetite, low energy, and discomfort …
self-esteem, lack of motivation, anhedonia, loss of appetite, low energy, and discomfort …
The habenula in psychiatric disorders: more than three decades of translational investigation
M Fakhoury - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
The habenula is an epithalamic structure located at the center of the dorsal diencephalic
conduction system, a pathway involved in linking forebrain to midbrain regions. Composed …
conduction system, a pathway involved in linking forebrain to midbrain regions. Composed …