Importance Annually in the United States, at least 3.5 million people seek medical attention
for traumatic brain injury (TBI). The development of therapies for TBI is limited by the …

Traumatic brain injury (TBI) can initiate progressive injury responses, which are linked to
increased risk of neurodegenerative diseases known as “tauopathies.” Increased post-TBI …

Importance Approximately one-third of military personnel who deploy for combat operations
sustain 1 or more traumatic brain injuries (TBIs), which increases the risk for chronic …

Traumatic brain injury (TBI) is a cause of death and disability and can lead to tauopathy-
related dementia at an early age. Pathologically, TBI results in axonal injury that is coupled …

The objective of this study was to investigate the diagnostic value of serum tau protein in
determining the severity of traumatic brain injury in patients with mild traumatic brain injury …

Plasma tau and glial fibrillary acidic protein (GFAP) are promising biomarkers for identifying
traumatic brain injury (TBI) patients with intracranial trauma on computed tomography (CT) …

Following traumatic brain injury, the neuronally-localized intracellular protein MAP-tau is
proteolytically cleaved (C-tau) and gains access to cerebrospinal fluid (CSF) and serum. The …

Study Objective: Intracranial injuries (ICI) are associated with high mortality and morbidity.
Unfortunately, tools for diagnosis and risk stratification of ICIs are limited in the emergency …

OBJECTIVES: Our objective was to determine if the biomarker for axonal injury, serum
cleaved tau (C-tau), predicts postconcussion syndrome (PCS) in adults after mild traumatic …

Objective: We investigated if tau, microtubular binding protein, in serum and ventricular CSF
(vCSF) in patients with severe traumatic brain injury (TBI) during the initial posttraumatic …