DNA base-pairing is the central interaction in DNA assembly. However, this simple four-
letter (A–T and G–C) language makes it difficult to create complex structures without using a …

Naturally existing biological systems, from the simplest unicellular diatom to the most
sophisticated organ such as the human brain, are functional self-assembled architectures …

The inherent properties of DNA as a stable polymer with unique affinity for partner molecules
determined by the specific Watson–Crick base pairing makes it an ideal component in self …

Highlights•New assembly approaches of DNA nanostructures with increased complexity.•
Biotechnological approaches for improved scalability of DNA assembly.•Blunt-end stacking …

We present a method in which a small molecule template is used to access a single DNA
nanostructure from a library of multiple assemblies. DNA building blocks 2 and 2 ', in which …

Nature uses a combination of non-covalent interactions to create a hierarchy of complex
systems from simple building blocks. One example is the selective association of the …

Conspectus DNA is an attractive polymer building material for nanodevices and
nanostructures due to its ability for self-recognition and self-assembly. Assembly relies on …

Engineering the assembly of nanoscale objects into complex and prescribed structures
requires control over their binding properties. Such control might benefit from a well-defined …

DNA has been used in the construction of a variety of nanoscale structures. Of these,
designed cage-like structures of sizes ranging from∼ 10 to∼ 100 nm and molecular weights …

Molecular self-assembly is a promising approach to the preparation of nanostructures. DNA,
in particular, shows great potential to be a superb molecular system. Synthetic DNA …