Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular
and cellular dysfunction that plays a major role in ageing and most age-related and …

Enhanced formation of reactive oxygen species (ROS) leads to tissue dysfunction and
damage in a number of pathological conditions. ROS oxidize the lipids to generate …

Lipid peroxidation (LPO) has been shown to induce disturbance of membrane organization
and functional loss and modification of proteins and DNA bases, and it has been implicated …

Physical and emotional stress, metabolic alterations, carcinogenesis or inflammation are
conditions that can trigger oxidative stress, which is defined as a balance shift of redox …

Lipid peroxidation has been implicated in the etiology of several diseases. The process of
lipid peroxidation can be initiated by a variety of oxidants, including H2O2, superoxide, and …

Since the discovery of oxidized phospholipids (OxPL) and their implication as modulators of
inflammation in cardiovascular disease, roles for these lipid oxidation products have been …

The central nervous system (CNS) is one of the most metabolically active organs and is
characterized by elevated oxygen requirements, while it possesses a diminished anti …

Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …

Lipid peroxidation is a free radical initiated chain oxidation of unsaturated lipids. With
respect to the ubiquity of unsaturated fatty acids in the cellular membranes, the peroxidative …

Apparently nature uses the unique sensitivity of polyunsaturated fatty acids (PUFAs) versus
oxygen to generate chemical signals if the surface of a cell is influenced by an outside or …