A compressibility and compactibility study of real tableting mixtures: The impact of wet and dry granulation versus a direct tableting mixture
M Šantl, I Ilić, F Vrečer, S Baumgartner - International journal of …, 2011 - Elsevier
The purpose of this study was to investigate the influence of various powder agglomeration
processes on tableting mixture flow and compaction properties. Four different granulation …
processes on tableting mixture flow and compaction properties. Four different granulation …
[PDF][PDF] A compressibility and compactibility study of real tableting mixtures: the effect of granule particle size
M Šantl, I Ilić, F Vrečer, S Baumgartner - Acta pharmaceutica, 2012 - sciendo.com
This study investigates the effect of particle size on the compression characteristics of wet-
(fluid-bed granulation–FBG) and dry-granulated (slugging–DGS) tableting mixtures. Particle …
(fluid-bed granulation–FBG) and dry-granulated (slugging–DGS) tableting mixtures. Particle …
Systematic study of paracetamol powder mixtures and granules tabletability: Key role of rheological properties and dynamic image analysis
O Macho, Ľ Gabrišová, J Brokešová… - International Journal of …, 2021 - Elsevier
The aim of this systematic study was to analyze the granulometric and rheological behavior
of tableting mixtures in relation to tabletability by single tablet and lab-scale batch …
of tableting mixtures in relation to tabletability by single tablet and lab-scale batch …
New insights into segregation during tabletting
S Lakio, S Siiriä, H Räikkönen, S Airaksinen… - International journal of …, 2010 - Elsevier
The aim of this study was to evaluate how different granule size distributions affect the tablet
compression process. The emphasis was on developing new analytic methods for …
compression process. The emphasis was on developing new analytic methods for …
The effect of particle fragmentation and deformation on the interparticulate bond formation process during powder compaction
M Eriksson, G Alderborn - Pharmaceutical research, 1995 - Springer
Purpose. The compression behaviour and the compactability of particles have been studied.
In addition, an expression describing the bond strength over a tablet cross section was …
In addition, an expression describing the bond strength over a tablet cross section was …
[HTML][HTML] A classification system for tableting behaviors of binary powder mixtures
CC Sun - asian journal of pharmaceutical sciences, 2016 - Elsevier
The ability to predict tableting properties of a powder mixture from individual components is
of both fundamental and practical importance to the efficient formulation development of …
of both fundamental and practical importance to the efficient formulation development of …
Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction
It is well known that compression speed can have significant effects on the compaction
properties of pharmaceutical powders. This is a challenge during scale up and technology …
properties of pharmaceutical powders. This is a challenge during scale up and technology …
Unified compaction curve model for tensile strength of tablets made by roller compaction and direct compression
L Farber, KP Hapgood, JN Michaels, XY Fu… - International journal of …, 2008 - Elsevier
A model that describes the relationship between roller-compaction conditions and tablet
strength is proposed. The model assumes that compaction is cumulative during roller …
strength is proposed. The model assumes that compaction is cumulative during roller …
Particle size distribution and evolution in tablet structure during and after compaction
F Fichtner, Å Rasmuson, G Alderborn - International journal of …, 2005 - Elsevier
The objective of this study was to investigate the effect of the distribution in size of free-
flowing particles for the evolution in tablet structure and tablet strength. For sucrose and …
flowing particles for the evolution in tablet structure and tablet strength. For sucrose and …
[HTML][HTML] Formulation design of granules prepared by wet granulation method using a multi-functional single-punch tablet press to avoid tableting failures
T Osamura, Y Takeuchi, R Onodera, M Kitamura… - asian journal of …, 2018 - Elsevier
We previously determined “Tableting properties” by using a multi-functional single-punch
tablet press (GTP-1). We plotted “Compactability” on the x-axis against “Manufacturability” …
tablet press (GTP-1). We plotted “Compactability” on the x-axis against “Manufacturability” …