Emulating host-microbiome ecosystem of human gastrointestinal tract in vitro
The human gut microbiome performs prodigious physiological functions such as production
of microbial metabolites, modulation of nutrient digestion and drug metabolism, control of …
of microbial metabolites, modulation of nutrient digestion and drug metabolism, control of …
Advances in modelling the human microbiome–gut–brain axis in vitro
CM Moysidou, RM Owens - Biochemical Society Transactions, 2021 - portlandpress.com
The human gut microbiome has emerged as a key player in the bidirectional communication
of the gut–brain axis, affecting various aspects of homeostasis and pathophysiology. Until …
of the gut–brain axis, affecting various aspects of homeostasis and pathophysiology. Until …
Organoids, organs-on-chips and other systems, and microbiota
S May, S Evans, L Parry - Emerging Topics in Life Sciences, 2017 - portlandpress.com
The human gut microbiome is considered an organ in its entirety and has been the subject
of extensive research due to its role in physiology, metabolism, digestion, and immune …
of extensive research due to its role in physiology, metabolism, digestion, and immune …
Dissecting Gut‐Microbial Community Interactions using a Gut Microbiome‐on‐a‐Chip
While the human gut microbiota has a significant impact on gut health and disease,
understanding of the roles of gut microbes, interactions, and collective impact of gut …
understanding of the roles of gut microbes, interactions, and collective impact of gut …
Gut-on-chip: Recreating human intestine in vitro
The human gut is important for food digestion and absorption, as well as a venue for a large
number of microorganisms that coexist with the host. Although numerous in vitro models …
number of microorganisms that coexist with the host. Although numerous in vitro models …
Intestinal stem cell-on-chip to study human host-microbiota interaction
F Siwczak, E Loffet, M Kaminska, H Koceva… - Frontiers in …, 2021 - frontiersin.org
The gut is a tubular organ responsible for nutrient absorption and harbors our intestinal
microbiome. This organ is composed of a multitude of specialized cell types arranged in …
microbiome. This organ is composed of a multitude of specialized cell types arranged in …
Ex vivo systems to study host–microbiota interactions in the gastrointestinal tract
G Roeselers, M Ponomarenko, S Lukovac… - Best Practice & …, 2013 - Elsevier
It is increasingly apparent that the microbial ecosystems in the mammalian gastrointestinal
tract play an intricate role in health and disease. There is a growing interest in the …
tract play an intricate role in health and disease. There is a growing interest in the …
Gut-on-chip for ecological and causal human gut microbiome research
S Moossavi, MC Arrieta, A Sanati-Nezhad… - Trends in …, 2022 - cell.com
There is a growing interest to understand if and how the gut microbiome is causally linked to
the pathogenesis and/or progression of diseases. While in vitro cell line models are …
the pathogenesis and/or progression of diseases. While in vitro cell line models are …
[HTML][HTML] Organoids and organs-on-chips: Insights into human gut-microbe interactions
The important and diverse roles of the gut microbiota in human health and disease are
increasingly recognized. The difficulty of inferring causation from metagenomic microbiome …
increasingly recognized. The difficulty of inferring causation from metagenomic microbiome …
Contributions of the microbiome to intestinal inflammation in a gut-on-a-chip
MS Jeon, YY Choi, SJ Mo, JH Ha, YS Lee, HU Lee… - Nano …, 2022 - Springer
The intestinal microbiome affects a number of biological functions of the organism. Although
the animal model is a powerful tool to study the relationship between the host and microbe …
the animal model is a powerful tool to study the relationship between the host and microbe …