Genetic variation in CHRNA5, the gene encoding the α5 nicotinic acetylcholine receptor
subunit, increases vulnerability to tobacco addiction and lung cancer, but the underlying …

Allelic variation in CHRNA3, the gene encoding the α3 nicotinic acetylcholine receptor
(nAChR) subunit, increases vulnerability to tobacco dependence and smoking-related …

Nicotine dependence is linked to single nucleotide polymorphisms in the CHRNB4-
CHRNA3-CHRNA5 gene cluster encoding the α3β4α5 nicotinic acetylcholine receptor …

NICOTINE affects many aspects of behaviour including learning and memory1, 2 through its
interaction with neuronal nicotinic acetylcholine receptors (nAChR). Functional nAChRs are …

Smoking is the most important preventable cause of morbidity and mortality worldwide.
Recent genome-wide association studies highlighted a human haplotype on chromosome …

Worldwide, 100 million people are expected to die this century from the consequences of
nicotine addiction, but nicotine is also known to enhance cognitive performance. Identifying …

Tobacco smoking results in more than five million deaths each year and accounts for∼ 90%
of all deaths from lung cancer. Nicotine, the major reinforcing component of tobacco smoke …

Tobacco smoking results in more than 5 million deaths each year and accounts for almost
90% of all deaths from lung cancer. Nicotine, the major reinforcing component of tobacco …

Objective Allelic variation in the α5 nicotinic acetylcholine receptor (nAChR) subunit gene,
CHRNA5, increases vulnerability to tobacco addiction. Here, we investigated the role of α5 …

NICOTINE obtained from tobacco can improve learning and memory on various tasks and
has been linked to arousal, attention, rapid information processing, working memory, and …