[HTML][HTML] On the origin of eating disorders: altered signaling between gut microbiota, adaptive immunity and the brain melanocortin system regulating feeding behavior

SO Fetissov, T Hökfelt - Current Opinion in Pharmacology, 2019 - Elsevier
Research in the field of gut microbiota–brain axis may contribute to clarifying the origin of
anorexia nervosa and bulimia, the two principal forms of eating disorders (ED). The initial …

Current aspects of the role of autoantibodies directed against appetite-regulating hormones and the gut microbiome in eating disorders

K Smitka, P Prochazkova, R Roubalova… - Frontiers in …, 2021 - frontiersin.org
The equilibrium and reciprocal actions among appetite-stimulating (orexigenic) and appetite-
suppressing (anorexigenic) signals synthesized in the gut, brain, microbiome and adipose …

Anorexia nervosa: Gut microbiota-immune-brain interactions

R Roubalová, P Procházková, H Papežová, K Smitka… - Clinical Nutrition, 2020 - Elsevier
Anorexia nervosa is a psychiatric disorder defined by an extremely low body weight, a
devastating fear of weight gain, and body image disturbance, however the etiopathogenesis …

Anorexia nervosa and autoimmune comorbidities: A bidirectional route?

MM Sirufo, LM Magnanimi, L Ginaldi… - CNS Neuroscience & …, 2022 - Wiley Online Library
Immunological dysfunctions in eating disorders have recently gained increasing scientific
attention. Furthermore, the reciprocal association between anorexia and autoimmune …

Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide α-MSH, at the origin of eating disorders

N Tennoune, P Chan, J Breton, R Legrand… - Translational …, 2014 - nature.com
The molecular mechanisms at the origin of eating disorders (EDs), including anorexia
nervosa (AN), bulimia and binge-eating disorder (BED), are currently unknown. Previous …

Emerging role of autoantibodies against appetite-regulating neuropeptides in eating disorders

SO Fetissov, MH Sinno, Q Coquerel, JC Do Rego… - Nutrition, 2008 - Elsevier
OBJECTIVE: Recent findings of autoantibodies directed against melanocortin peptides
suggest that these autoantibodies may represent a source of variability in peptidergic …

[HTML][HTML] Eating disorders: an evolutionary psychoneuroimmunological approach

MJ Rantala, S Luoto, T Krama, I Krams - Frontiers in psychology, 2019 - frontiersin.org
Eating disorders are evolutionarily novel conditions. They lead to some of the highest
mortality rates of all psychiatric disorders. Several evolutionary hypotheses have been …

Food matters: how the microbiome and gut–brain interaction might impact the development and course of anorexia nervosa

B Herpertz-Dahlmann, J Seitz, J Baines - European child & adolescent …, 2017 - Springer
Anorexia nervosa (AN) is one of the most common chronic illnesses in female adolescents
and exhibits the highest mortality risk of all psychiatric disorders. Evidence for the …

Gut microbiome-brain interactions in anorexia nervosa: Potential mechanisms and regulatory strategies

R Zhu, P Tian, H Zhang, G Wang, W Chen - Neuropharmacology, 2023 - Elsevier
Anorexia nervosa (AN) is a psychiatric disorder characterised by malnutrition, fear of weight
gain, and body image disturbances. The aetiology of AN is complex, and may involve …

A critical analysis of eating disorders and the gut microbiome

SM Terry, JA Barnett, DL Gibson - Journal of eating disorders, 2022 - Springer
The gut microbiota, also known as our “second brain” is an exciting frontier of research
across a multitude of health domains. Gut microbes have been implicated in feeding …