Crohn's disease (CD) is regarded as a lifelong progressive disease affecting all segments of
the intestinal tract and multiple organs. Based on genome-wide association studies (GWAS) …

Crohn's Disease (CD) is one of the predominant forms of inflammatory bowel disease (IBD).
A combination of genetic and non-genetic risk factors have been reported to contribute to the …

Inflammatory bowel disease (IBD) is a complex disease, resulting from abnormal immune
response to intestinal tract microbiota in genetically susceptible individuals. Crohn's disease …

Background After years of concentrated research efforts, the exact cause of Crohn's disease
(CD) remains unknown. Its accurate diagnosis, however, helps in management and …

Multiple genome-wide association studies (GWASs) and two large scale meta-analyses
have been performed for Crohn's disease and have identified 71 susceptibility loci. These …

Genome-wide association studies (GWAS) have identified hundreds of loci associated with
Crohns disease (CD), however, as with all complex diseases, deriving pathogenic …

Abstract Background and Aims Genome-wide association studies [GWAS] for inflammatory
bowel disease [IBD] have identified 240 risk variants. However, the benefit of understanding …

Genome-wide association studies have identified~ 170 loci associated with Crohn's disease
(CD) and defining which genes drive these association signals is a major challenge. The …

Genome-wide association studies have identified over 200 genetic loci associated with
inflammatory bowel disease; however, the mechanism of such a large amount of …

We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …