Entorhinal-retrosplenial circuits for allocentric-egocentric transformation of boundary coding

JBG van Wijngaarden, SS Babl, HT Ito - Elife, 2020 - elifesciences.org
Spatial navigation requires landmark coding from two perspectives, relying on viewpoint-
invariant and self-referenced representations. The brain encodes information within each …

Egocentric boundary vector tuning of the retrosplenial cortex

AS Alexander, LC Carstensen, JR Hinman… - Science …, 2020 - science.org
The retrosplenial cortex is reciprocally connected with multiple structures implicated in
spatial cognition, and damage to the region itself produces numerous spatial impairments …

Principles governing the integration of landmark and self-motion cues in entorhinal cortical codes for navigation

MG Campbell, SA Ocko, CS Mallory, IIC Low… - Nature …, 2018 - nature.com
To guide navigation, the nervous system integrates multisensory self-motion and landmark
information. We dissected how these inputs generate spatial representations by recording …

Transformation of the head-direction signal into a spatial code

A Peyrache, N Schieferstein, G Buzsáki - Nature communications, 2017 - nature.com
Animals integrate multiple sensory inputs to successfully navigate in their environments.
Head direction (HD), boundary vector, grid and place cells in the entorhinal-hippocampal …

The spatial memory pipeline: a model of egocentric to allocentric understanding in mammalian brains

B Uria, B Ibarz, A Banino, V Zambaldi, D Kumaran… - BioRxiv, 2020 - biorxiv.org
In the mammalian brain, allocentric representations support efficient self-location and
flexible navigation. A number of distinct populations of these spatial responses have been …

Environmental anchoring of head direction in a computational model of retrosplenial cortex

A Bicanski, N Burgess - Journal of Neuroscience, 2016 - Soc Neuroscience
Allocentric (world-centered) spatial codes driven by path integration accumulate error unless
reset by environmental sensory inputs that are necessarily egocentric (body-centered) …

Evidence for allocentric boundary and goal direction information in the human entorhinal cortex and subiculum

JP Shine, JP Valdes-Herrera, C Tempelmann… - Nature …, 2019 - nature.com
In rodents, cells in the medial entorhinal cortex (EC) and subiculum code for the allocentric
direction to environment boundaries, which is an important prerequisite for accurate …

Dissociation between postrhinal cortex and downstream parahippocampal regions in the representation of egocentric boundaries

X Gofman, G Tocker, S Weiss, CN Boccara, L Lu… - Current Biology, 2019 - cell.com
Navigation requires the integration of many sensory inputs to form a multi-modal cognitive
map of the environment, which is believed to be implemented in the hippocampal region by …

Sense of self impacts spatial navigation and hexadirectional coding in human entorhinal cortex

HJ Moon, B Gauthier, HD Park, N Faivre… - Communications …, 2022 - nature.com
Grid cells in entorhinal cortex (EC) encode an individual's location in space and rely on
environmental cues and self-motion cues derived from the individual's body. Body-derived …

Direct cortical inputs to hippocampal area CA1 transmit complementary signals for goal-directed navigation

JC Bowler, A Losonczy - Neuron, 2023 - cell.com
The subregions of the entorhinal cortex (EC) are conventionally thought to compute
dichotomous representations for spatial processing, with the medial EC (MEC) providing a …