Importance Whether neurodegeneration contributes to the early pathobiology of late-life
depression remains incompletely understood. Objective To investigate whether lower retinal …

Background Previous studies report that the thickness of the peripheral retinal nerve fiber
layer (RNFL) in individuals with Alzheimer's disease (AD) and mild cognitive impairment …

Importance Identifing potential screening tests for future cognitive decline is a priority for
developing treatments for and the prevention of dementia. Objective To examine the …

Importance The eye is a sensory organ that is easily accessible for imaging techniques,
allowing the measurement of the retinal nerve fiber layer (RNFL) thickness. The eye is part …

Backgrounds: Abnormal retinal nerve fiber layer (RNFL) thickness has been observed in
patients with Alzheimer's disease (AD) and therefore suggested to be a potential biomarker …

Background Retinal structural abnormalities have been found to serve as biomarkers for
cardiovascular disease (CVD). However, the association between retinal nerve fiber layer …

Currently, there is a lack of biomarkers to identify individuals in the early stages of
Alzheimer's disease (AD). A preponderance of evidence suggests that neurodegenerative …

Methods A total of 30 patients with major depressive disorder and 30 age-and sex-matched
controls were recruited. Using optical coherence tomography (OCT), the peripapillary RNFL …

Purpose To compare peripapillary retinal nerve fiber layer (RNFL) thickness among healthy
adults by race and ethnicity and to identify determinants of RNFL thickness. Design …

purpose. The brain areas that are responsible for cognitive functioning have the same
embryonic origin as the retina. The association between cognitive functioning and retinal …