Targeting specific cell signaling transduction pathways by dietary and medicinal phytochemicals in cancer chemoprevention

VS Neergheen, T Bahorun, EW Taylor, LS Jen… - Toxicology, 2010 - Elsevier
Natural phytochemicals derived from dietary sources or medicinal plants have gained
significant recognition in the potential management of several human clinical conditions …

Cell signaling pathways altered by natural chemopreventive agents

FH Sarkar, Y Li - … Research/Fundamental and Molecular Mechanisms of …, 2004 - Elsevier
Epidemiological studies have indicated a significant difference in the incidence of cancers
among ethnic groups, who have different lifestyles and have been exposed to different …

Potential mechanisms of action of dietary phytochemicals for cancer prevention by targeting cellular signaling transduction pathways

H Chen, RH Liu - Journal of agricultural and food chemistry, 2018 - ACS Publications
Cancer is a severe health problem that significantly undermines life span and quality.
Dietary approach helps provide preventive, nontoxic, and economical strategies against …

[HTML][HTML] Role of phytochemicals in cancer chemoprevention: Insights

BP George, R Chandran, H Abrahamse - Antioxidants, 2021 - mdpi.com
Cancer is a condition where the body cells multiply in an uncontrollable manner.
Chemoprevention of cancer is a broad term that describes the involvement of external …

Phytochemicals as chemo-preventive agents and signaling molecule modulators: current role in cancer therapeutics and inflammation

MB Ahmed, SU Islam, AAA Alghamdi… - International Journal of …, 2022 - mdpi.com
Cancer is one of the deadliest non communicable diseases. Numerous anticancer
medications have been developed to target the molecular pathways driving cancer …

[HTML][HTML] Pharmacotherapeutic potential of phytochemicals: Implications in cancer chemoprevention and future perspectives

V Kaur, M Kumar, A Kumar, K Kaur, VS Dhillon… - Biomedicine & …, 2018 - Elsevier
Cancer is a leading cause of disease burden throughout the world. Many cancers develop
as a result of exposure to both lifestyle and environmental factors that are potentially …

[HTML][HTML] Cancer chemoprevention: A strategic approach using phytochemicals

M Swetha, CK Keerthana, TP Rayginia… - Frontiers in …, 2022 - frontiersin.org
Cancer chemoprevention approaches are aimed at preventing, delaying, or suppressing
tumor incidence using synthetic or natural bioactive agents. Mechanistically …

[HTML][HTML] Redox-Sensitive Transcription Factors as Prime Targets for Chemoprevention with Anti-Inflammatory and Antioxidative Phytochemicals–

YJ Surh, JK Kundu, HK Na, JS Lee - The Journal of nutrition, 2005 - Elsevier
Oxidative stress has been implicated in various pathological conditions including cancer.
However, the human body has an intrinsic ability to fight against oxidative stress. A wide …

Cancer prevention with promising natural products: mechanisms of action and molecular targets

P Pratheeshkumar, C Sreekala, Z Zhang… - Anti-Cancer Agents …, 2012 - ingentaconnect.com
Cancer is the second leading cause of death worldwide. There is greater need for more
effective and less toxic therapeutic and preventive strategies. Natural products are becoming …

Cancer chemoprevention: current state of the art

KR Landis-Piwowar, NR Iyer - Cancer growth and metastasis, 2014 - journals.sagepub.com
The aim of cancer chemoprevention is disruption or delay of the molecular pathways that
lead to carcinogenesis. Chemopreventive blocking and/or suppressing agents disrupt the …