Extracellular matrix dynamics: tracking in biological systems and their implications
The extracellular matrix (ECM) constitutes the main acellular microenvironment of cells in
almost all tissues and organs. The ECM not only provides mechanical support, but also …
almost all tissues and organs. The ECM not only provides mechanical support, but also …
Extracellular matrix in lung development, homeostasis and disease
The lung's unique extracellular matrix (ECM), while providing structural support for cells, is
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …
Extracellular matrix dynamics in development and regenerative medicine
The extracellular matrix (ECM) regulates cell behavior by influencing cell proliferation,
survival, shape, migration and differentiation. Far from being a static structure, the ECM is …
survival, shape, migration and differentiation. Far from being a static structure, the ECM is …
[HTML][HTML] Chronic lung diseases: entangled in extracellular matrix
JK Burgess, MC Harmsen - European Respiratory Review, 2022 - Eur Respiratory Soc
The extracellular matrix (ECM) is the scaffold that provides structure and support to all
organs, including the lung; however, it is also much more than this. The ECM provides …
organs, including the lung; however, it is also much more than this. The ECM provides …
[HTML][HTML] Engineering ECM signals into biomaterials
RJ Wade, JA Burdick - Materials Today, 2012 - Elsevier
Historically, tissue engineering focused primarily on the delivery of soluble factors within
relatively static scaffolds; yet, increasing evidence indicates that the native, dynamic three …
relatively static scaffolds; yet, increasing evidence indicates that the native, dynamic three …
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
TR Cox, JT Erler - Disease models & mechanisms, 2011 - journals.biologists.com
Dynamic remodeling of the extracellular matrix (ECM) is essential for development, wound
healing and normal organ homeostasis. Life-threatening pathological conditions arise when …
healing and normal organ homeostasis. Life-threatening pathological conditions arise when …
The extracellular matrix–the under‐recognized element in lung disease?
The lung is composed of airways and lung parenchyma, and the extracellular matrix (ECM)
contains the main building blocks of both components. The ECM provides physical support …
contains the main building blocks of both components. The ECM provides physical support …
Matrix, mesenchyme, and mechanotransduction
DJ Tschumperlin - Annals of the American Thoracic Society, 2015 - atsjournals.org
The extracellular matrix (ECM) of the lung serves as both a scaffold for resident cells and a
mechanical support for respiratory function. The ECM is deposited during development and …
mechanical support for respiratory function. The ECM is deposited during development and …
The instructive extracellular matrix of the lung: basic composition and alterations in chronic lung disease
G Burgstaller, B Oehrle, M Gerckens… - European …, 2017 - Eur Respiratory Soc
The pulmonary extracellular matrix (ECM) determines the tissue architecture of the lung, and
provides mechanical stability and elastic recoil, which are essential for physiological lung …
provides mechanical stability and elastic recoil, which are essential for physiological lung …
Exploring the extracellular matrix in health and disease using proteomics
IN Taha, A Naba - Essays in biochemistry, 2019 - portlandpress.com
The extracellular matrix (ECM) is a complex assembly of hundreds of proteins that
constitutes the scaffold of multicellular organisms. In addition to providing architectural and …
constitutes the scaffold of multicellular organisms. In addition to providing architectural and …