[HTML][HTML] The role of extracellular vesicles in the physiological and pathological regulation of the blood–brain barrier

S Busatto, G Morad, P Guo, MA Moses - FASEB BioAdvances, 2021 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) are a subclass of biological nanoparticles secreted by most cell
types. Once secreted, EVs can travel long distances to deliver their content to target cells …

Emerging roles of extracellular vesicles in the central nervous system: Physiology, pathology, and therapeutic perspectives

Y Gassama, A Favereaux - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Extracellular vesicles or EVs are secreted by most, if not all, eukaryote cell types and
recaptured by neighboring or distant cells. Their cargo, composed of a vast diversity of …

Brain-derived extracellular vesicles in health and disease: a methodological perspective

S Brenna, C Krisp, HC Altmeppen, T Magnus… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are double membrane structures released by presumably all cell
types that transport and deliver lipids, proteins, and genetic material to near or distant …

Extracellular vesicles at CNS barriers: Mode of action

EM Krämer-Albers - Current Opinion in Neurobiology, 2022 - Elsevier
The exchange of molecules between the brain and periphery is limited by cellular barriers
such as the blood–brain barrier (BBB) and the blood-CSF barrier (BCB). Extracellular …

Extracellular vesicles through the blood–brain barrier: A review

HM Ramos-Zaldívar, I Polakovicova… - Fluids and Barriers of …, 2022 - Springer
Extracellular vesicles (EVs) are particles naturally released from cells that are delimited by a
lipid bilayer and are unable to replicate. How the EVs cross the Blood–Brain barrier (BBB) in …

Engineered extracellular vesicles as brain therapeutics

MM Lino, S Simoes, F Tomatis, I Albino… - Journal of Controlled …, 2021 - Elsevier
Extracellular vesicles (EVs) are communication channels between different cell types in the
brain, between the brain and the periphery and vice-versa, playing a fundamental role in …

Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases

D Rufino-Ramos, PR Albuquerque, V Carmona… - Journal of Controlled …, 2017 - Elsevier
Extracellular vesicles (EVs) are cell-derived membrane vesicles virtually secreted by all
cells, including brain cells. EVs are a major term that includes apoptotic bodies …

Strategies for the use of extracellular vesicles for the delivery of therapeutics

S Sil, RS Dagur, K Liao, ES Peeples, G Hu… - Journal of Neuroimmune …, 2020 - Springer
Extracellular vesicles (EVs) are nanosized, membrane-bound vesicles released from
eukaryotic and prokaryotic cells that can transport cargo containing DNA, RNA, lipids and …

Extracellular vesicles, from the pathogenesis to the therapy of neurodegenerative diseases

X Xia, Y Wang, JC Zheng - Translational Neurodegeneration, 2022 - Springer
Extracellular vesicles (EVs) are small bilipid layer-enclosed vesicles that can be secreted by
all tested types of brain cells. Being a key intercellular communicator, EVs have emerged as …

Therapeutically harnessing extracellular vesicles

L Cheng, AF Hill - Nature Reviews Drug Discovery, 2022 - nature.com
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …