Particulate matter in COPD pathogenesis: an overview

M Kaur, J Chandel, J Malik, AS Naura - Inflammation Research, 2022 - Springer
Chronic obstructive pulmonary disease (COPD) is a progressive lung disorder with
substantial patient burden and leading cause of death globally. Cigarette smoke remains to …

Particulate matter air pollution exposure: role in the development and exacerbation of chronic obstructive pulmonary disease

SH Ling, SF van Eeden - International journal of chronic …, 2009 - Taylor & Francis
Due to the rapid urbanization of the world population, a better understanding of the
detrimental effects of exposure to urban air pollution on chronic lung disease is necessary …

[HTML][HTML] Fine particulate matter in acute exacerbation of COPD

L Ni, CC Chuang, L Zuo - Frontiers in physiology, 2015 - frontiersin.org
Chronic obstructive pulmonary disease (COPD) is a common airway disorder. In particular,
acute exacerbations of COPD (AECOPD) can significantly reduce pulmonary function. The …

[HTML][HTML] Lung macrophage functional properties in chronic obstructive pulmonary disease

K Akata, SF van Eeden - International journal of molecular sciences, 2020 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is caused by the chronic exposure of the
lungs to toxic particles and gases. These exposures initiate a persistent innate and adaptive …

[HTML][HTML] Recent evidence from omic analysis for redox signalling and mitochondrial oxidative stress in COPD

S Mumby, IM Adcock - Journal of inflammation, 2022 - Springer
COPD is driven by exogenous and endogenous oxidative stress derived from inhaled
cigarette smoke, air pollution and reactive oxygen species from dysregulated mitochondria …

[HTML][HTML] A mitochondrial perspective of chronic obstructive pulmonary disease pathogenesis

MJ Kang, GS Shadel - Tuberculosis and Respiratory Diseases, 2016 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) encompasses several clinical syndromes,
most notably emphysema and chronic bronchitis. Most of the current treatments fail to …

Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease

T Yoshida, RM Tuder - Physiological reviews, 2007 - journals.physiology.org
Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …

Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine

CA Brandsma, M Van den Berge… - The Journal of …, 2020 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) is a devastating lung disease with a high
personal and societal burden. Exposure to toxic particles and gases, including cigarette …

Particulate matter induces tissue oxinflammation: from mechanism to damage

G Valacchi, N Magnani, B Woodby… - Antioxidants & Redox …, 2020 - liebertpub.com
Significance: Oxidative stress and oxidative damage are central hypothetical mechanisms
for the adverse effects of airborne particulate matter (PM). Activation of inflammatory cells …

Integrative characterization of fine particulate matter-induced chronic obstructive pulmonary disease in mice

Q Li, J Sun, X Chen, S Li, Y Wang, C Xu, J Zhao… - Science of the total …, 2020 - Elsevier
The impacts of ambient fine particulate matter (PM 2.5) on public health are a worldwide
concern. Epidemiological evidence has shown that PM 2.5-triggered inflammatory cascades …