Genome-wide mapping of G-quadruplex structures with CUT&Tag
J Lyu, R Shao, PY Kwong Yung… - Nucleic acids …, 2022 - academic.oup.com
Single-stranded genomic DNA can fold into G-quadruplex (G4) structures or form DNA: RNA
hybrids (R loops). Recent evidence suggests that such non-canonical DNA structures affect …
hybrids (R loops). Recent evidence suggests that such non-canonical DNA structures affect …
[HTML][HTML] G-quadruplex DNA structures in human stem cells and differentiation
The establishment of cell identity during embryonic development involves the activation of
specific gene expression programmes and is underpinned by epigenetic factors including …
specific gene expression programmes and is underpinned by epigenetic factors including …
[HTML][HTML] Promoter G-quadruplex folding precedes transcription and is controlled by chromatin
Background Four-stranded G-quadruplexes (G4s) are DNA secondary structures in the
human genome that are primarily found in active promoters associated with elevated …
human genome that are primarily found in active promoters associated with elevated …
Structure, location and interactions of G‐quadruplexes
JL Huppert - The FEBS journal, 2010 - Wiley Online Library
Four‐stranded G‐rich DNA structures called G‐quadruplexes have been the subject of
increasing interest recently. Experimental and computational techniques have been used to …
increasing interest recently. Experimental and computational techniques have been used to …
[HTML][HTML] G-quadruplex structures are stable and detectable in human genomic DNA
EYN Lam, D Beraldi, D Tannahill… - Nature …, 2013 - nature.com
The G-quadruplex is an alternative DNA structural motif that is considered to be functionally
important in the mammalian genome for transcriptional regulation, DNA replication and …
important in the mammalian genome for transcriptional regulation, DNA replication and …
High-throughput sequencing of DNA G-quadruplex structures in the human genome
VS Chambers, G Marsico, JM Boutell… - Nature …, 2015 - nature.com
Abstract G-quadruplexes (G4s) are nucleic acid secondary structures that form within
guanine-rich DNA or RNA sequences. G4 formation can affect chromatin architecture and …
guanine-rich DNA or RNA sequences. G4 formation can affect chromatin architecture and …
[HTML][HTML] R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
Abstract G-quadruplex (G4) is a noncanonical secondary structure of DNA or RNA which
can enhance or repress gene expression, yet the underlying molecular mechanism remains …
can enhance or repress gene expression, yet the underlying molecular mechanism remains …
Genome-wide mapping of endogenous G-quadruplex DNA structures by chromatin immunoprecipitation and high-throughput sequencing
R Hänsel-Hertsch, J Spiegel, G Marsico, D Tannahill… - Nature protocols, 2018 - nature.com
G-rich DNA sequences can form four-stranded G-quadruplex (G4) secondary structures and
are linked to fundamental biological processes such as transcription, replication and …
are linked to fundamental biological processes such as transcription, replication and …
[HTML][HTML] Single-cell mapping of DNA G-quadruplex structures in human cancer cells
Abstract G-quadruplexes (G4s) are four-stranded DNA secondary structures that form in
guanine-rich regions of the genome. G4s have important roles in transcription and …
guanine-rich regions of the genome. G4s have important roles in transcription and …
Conserved elements with potential to form polymorphic G-quadruplex structures in the first intron of human genes
J Eddy, N Maizels - Nucleic acids research, 2008 - academic.oup.com
To understand how potential for G-quadruplex formation might influence regulation of gene
expression, we examined the 2 kb spanning the transcription start sites (TSS) of the 18 217 …
expression, we examined the 2 kb spanning the transcription start sites (TSS) of the 18 217 …