Fluorescent DNA probes were prepared in a modular approach using the “click” post-
synthetic modification strategy. The new glycol-based module and DNA building block place …

Double‐labeled oligonucleotide probes containing fluorophores interacting by energy‐
transfer mechanisms are essential for modern bioanalysis, molecular diagnostics, and in …

The azides 1 and 2 bearing a phenoxazinium and a coumarin fluorophore, respectively,
were applied in postsynthetic “click”-type bioconjugation and coupled to oligonucleotides …

An orange‐and a red‐emitting tetrazine‐modified cyanine‐styryl dyes were synthesized for
bioorthogonal labelling of DNA by means of the Diels‐Alder reaction with inverse electron …

The chromophore of thiazole orange (TO) and its derivative TO3 were incorporated
synthetically as base surrogates into oligonucleotides using automated phosphoramidite …

Photochemical & Photobiological Sciences Page 1 Photochemical & Photobiological Sciences
COMMUNICATION Cite this: Photochem. Photobiol. Sci., 2013, 12, 722 Received 2nd …

Fluorescently labeled oligonucleotides are commonly employed as probes to detect specific
DNA or RNA sequences in homogeneous solution. Useful probes should experience strong …

Unsymmetrical cyanine dyes, such as thiazole orange, are useful for the detection of nucleic
acids with fluorescence because they dramatically enhance the fluorescence upon binding …

The design of a fluorescent probe in which the fluorescence is switched off when the probe
does not recognize the target nucleic acid is very important for the establishment of a nucleic …

We have designed a doubly thiazole orange labeled nucleoside showing high fluorescence
intensity for a hybrid with the target DNA and effective quenching for a single-stranded state …