This study aimed to evaluate the attenuating effect of Lactobacillus plantarum DP189 on α-
synuclein (α-SYN) aggregates in the substantia nigra (SN) of Parkinson's disease (PD) mice …

Parkinson's disease (PD) is a neurodegenerative disease (NDD) with high and ongoing
morbidity, bringing heavy burdens to PD patients seriously. Finding neurotrophic drugs still …

Recent studies have demonstrated that disturbances in the gut microbiota and microbiota-
derived metabolites contribute to the pathogenesis of Parkinson's disease (PD), suggesting …

Parkinson's disease (PD) is a neurodegenerative disease characterized by motor deficits
and marked neuroinflammation in various brain regions. The pathophysiology of PD is …

Gut microbiota is closely related to the Parkinson's disease (PD) pathogenesis. Additionally,
aggregation of α-synuclein (α-syn) is central to PD pathogenesis. Here we identified the …

Considerable evidence suggests that insulin resistance is closely linked to Parkinson's
disease (PD), leading to agents aiming at treating diabetes can be regarded as new …

Chicoric acid (CA), a polyphenolic acid obtained from chicory and purple coneflower
(Echinacea purpurea), has been regarded as a nutraceutical to combat inflammation …

Probiotic intervention has beneficial effects on host brain function and behavior via
regulating microbiota-gut-brain axis; however, the underlying mechanism is not yet …

Background Parkinson's disease (PD) is a prevalent neurodegenerative disorder, displaying
not only well-known motor deficits but also gastrointestinal dysfunctions. Consistently, it has …

Probiotics and prebiotics have received attention in alleviating neurodegenerative diseases.
Lactobacillus plantarum (L. plantarum) 69-2 was combined with galactooligosaccharides …