Reactive oxygen species bridge the gap between chronic inflammation and tumor development

W Yu, Y Tu, Z Long, J Liu, D Kong… - Oxidative medicine …, 2022 - Wiley Online Library
According to numerous animal studies, adverse environmental stimuli, including physical,
chemical, and biological factors, can cause low‐grade chronic inflammation and subsequent …

The two faces of reactive oxygen species in cancer

CR Reczek, NS Chandel - Annual review of cancer biology, 2017 - annualreviews.org
Reactive oxygen species (ROS), now appreciated for their cellular signaling capabilities,
have a dual role in cancer. On the one hand, ROS can promote protumorigenic signaling …

Reactive oxygen species: the achilles' heel of cancer cells?

X Cui - Antioxidants & redox signaling, 2012 - liebertpub.com
Cancer development, progression, and metastasis are multistep processes. Accumulating
evidence suggests that reactive oxygen species (ROS) are critically involved in cancer cell …

Reactive oxygen species in cancer

GY Liou, P Storz - Free radical research, 2010 - Taylor & Francis
Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …

Reactive oxygen species: a key constituent in cancer survival

S Kumari, AK Badana, RR Malla - Biomarker insights, 2018 - journals.sagepub.com
Background: Cancer is one of the major heterogeneous disease with high morbidity and
mortality with poor prognosis. Elevated levels of reactive oxygen species (ROS), alteration in …

ROS signalling in the biology of cancer

JN Moloney, TG Cotter - Seminars in cell & developmental biology, 2018 - Elsevier
Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

[HTML][HTML] Dual role of reactive oxygen species and their application in cancer therapy

R Huang, H Chen, J Liang, Y Li, J Yang, C Luo… - Journal of …, 2021 - ncbi.nlm.nih.gov
Reactive oxygen species (ROS) play a dual role in the initiation, development, suppression,
and treatment of cancer. Excess ROS can induce nuclear DNA, leading to cancer initiation …

ROS generation and antioxidant defense systems in normal and malignant cells

AV Snezhkina, AV Kudryavtseva… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Inflammation, DAMPs, tumor development, and progression: a vicious circle orchestrated by redox signaling

P Castellani, E Balza, A Rubartelli - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Increasing evidence indicates that cancer development and progression are
promoted by the joint action of redox distress and inflammation, supporting the potential …

[HTML][HTML] Role of reactive oxygen species in cancer progression: molecular mechanisms and recent advancements

V Aggarwal, HS Tuli, A Varol, F Thakral, MB Yerer… - Biomolecules, 2019 - mdpi.com
Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …