Pharmacology of nicotine: addiction, smoking-induced disease, and therapeutics

NL Benowitz - Annual review of pharmacology and toxicology, 2009 - annualreviews.org
Nicotine sustains tobacco addiction, a major cause of disability and premature death.
Nicotine binds to nicotinic cholinergic receptors, facilitating neurotransmitter release and …

Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction

NL Benowitz - Clinical Pharmacology & Therapeutics, 2008 - Wiley Online Library
Understanding the basic and clinical pharmacology of nicotine provides a basis for
improved prevention and treatment of tobacco addiction. Nicotine acts on nicotinic …

Neurobiology of nicotine addiction: implications for smoking cessation treatment

NL Benowitz - The American journal of medicine, 2008 - Elsevier
Nicotine sustains addictive tobacco use, which in turn causes much premature disability and
death. The essence of drug addiction is loss of control of drug use. Molecular biology studies …

Pharmacology of nicotine: addiction and therapeutics.

NL Benowitz - Annual review of pharmacology and toxicology, 1996 - europepmc.org
Nicotine maintains tobacco addiction and has therapeutic utility to aid smoking cessation
and possibly to treat other medical diseases. Nicotine acts on nicotinic cholinergic receptors …

[图书][B] Nicotine addiction: principles and management

CT Orleans, JD Slade - 1993 - books.google.com
Despite persistent warnings from the medical profession about the health risks involved in
cigarette smoking, millions of people continue to smoke cigarettes. With contributions from …

Current pharmacological treatments for nicotine dependence

TP George, SS O'Malley - Trends in pharmacological sciences, 2004 - cell.com
There are nearly 1.1 billion users of nicotine and tobacco products worldwide. Tobacco use
through cigarette smoking is the leading preventable cause of death in the world and kills …

[图书][B] Nicotine safety and toxicity

NL Benowitz - 1998 - books.google.com
Nicotine has been developed as a medication to assist smoking cessation, and is being
considered as a possible drug for long-term maintenance of non-smoking. It is also …

[图书][B] Molecular mechanisms associated with nicotine pharmacology and dependence

CD Fowler, JR Turner, M Imad Damaj - 2020 - Springer
Tobacco dependence is a leading cause of preventable disease and death worldwide.
Nicotine, the main psychoactive component in tobacco cigarettes, has also been garnering …

Nicotine addiction

NL Benowitz - Primary Care: Clinics in Office Practice, 1999 - Elsevier
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Nicotine medications for smoking cessation

JE Henningfield - New England Journal of Medicine, 1995 - Mass Medical Soc
Cigarettes are among the most addicting products known, and the vast majority of people
who quit smoking relapse within days. 1, 2 In the United States, less than 10 percent of the …