Mitophagy has distinct functions, which can lead to either protection or damage of tissues.
Though current evidence indicated that NaF triggers mitophagy, the role and regulation of …

Abstract Aflatoxin B 1 (AFB 1) can cause oxidative stress leading to mitochondrial damage
and subsequent liver injury. Although it is well-known that damaged mitochondria are …

Objective Fine particulate matter (PM2. 5) is a source of pollution worldwide, that causes
inflammation and liver fibrosis. Melatonin, as the predominant hormone secreted by the …

Due to the high abundance in the Earth's crust and industrial application, fluoride is widely
present in our living environment. However, excessive fluoride exposure causes toxicity in …

Mitochondria damage plays a critical role in acetaminophen (APAP)-induced necrosis and
liver injury. Cells can adapt and protect themselves by removing damaged mitochondria via …

Hepatic ischemia/reperfusion (I/R) injury is a major concern in liver surgery settings.
Mitochondria are critical targets or the origin of tissue injury, particularly I/R injury …

Mitochondrial reactive oxygen species (ROS) production has been implicated in the
pathogenesis of fluoride toxicity in liver. Melatonin, an indolamine synthesized in the pineal …

Activation of nucleotide-binding domain leucine-rich repeat containing family pyrin domain
containing 3 (NLRP3) inflammasome in Kupffer cells (KCs) contributes significantly to …

Silver nanoparticles (AgNPs) have wide clinical applications because of their excellent
antibacterial properties; however, they can cause liver inflammation in animals …

Objectives Mitophagy is considered to be a key mechanism in the pathogenesis of intestinal
ischaemic reperfusion (IR) injury. NOD‐like receptor X1 (NLRX1) is located in the …