Evaluation of Recombinant Leptospira Antigen-Based Enzyme-Linked Immunosorbent Assays for the Serodiagnosis of Leptospirosis

B Flannery, D Costa, FP Carvalho… - Journal of clinical …, 2001 - Am Soc Microbiol
There is an urgent need for development of new serodiagnostic strategies for leptospirosis,
an emerging zoonosis with worldwide distribution. We have evaluated the diagnostic utility …

Simple latex agglutination assay for rapid serodiagnosis of human leptospirosis

HL Smits, MAWG van der Hoorn… - Journal of Clinical …, 2000 - Am Soc Microbiol
ABSTRACT A newly developed latex agglutination assay for the detection of genus-specific
Leptospira antibodies in human sera was evaluated. The assay is performed by mixing, on …

International Multicenter Evaluation of the Clinical Utility of a Dipstick Assay for Detection ofLeptospira-Specific Immunoglobulin M Antibodies in Human Serum …

HL Smits, YV Ananyina, A Chereshsky… - Journal of clinical …, 1999 - Am Soc Microbiol
We performed a multicenter evaluation of a robust and easily performed dipstick assay for
the serodiagnosis of human leptospirosis. The assay is aimed at the detection of Leptospira …

Evaluation of an in-house ELISA using the intermediate species Leptospira fainei for diagnosis of leptospirosis

P Bourhy, M Vray, M Picardeau - Journal of medical …, 2013 - microbiologyresearch.org
Leptospirosis is recognized as an emerging zoonotic disease generally affecting urban
slums in developing countries and tropical regions. A combination of non-specific symptoms …

[HTML][HTML] Laboratory diagnosis of leptospirosis: a challenge

D Musso, B La Scola - Journal of Microbiology, Immunology and Infection, 2013 - Elsevier
Leptospirosis is caused by pathogenic bacteria called leptospires that are transmitted
directly or indirectly from animals to humans. It occurs worldwide but is most common in …

Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene

RA Stoddard, JE Gee, PP Wilkins… - … and infectious disease, 2009 - Elsevier
Rapid diagnosis of leptospirosis, through culture and/or serology, can be difficult without
proper expertise and is often delayed because of the length of time required to obtain …

Evaluation of a commercial latex agglutination assay for serological diagnosis of leptospirosis

C Hull-Jackson, MB Glass, MD Ari… - Journal of clinical …, 2006 - Am Soc Microbiol
Leptospirosis is a febrile zoonosis of worldwide distribution. A latex agglutination assay was
evaluated in two studies, the first using a panel of well-characterized sera from patients with …

Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis

MD Bajani, DA Ashford, SL Bragg… - Journal of clinical …, 2003 - Am Soc Microbiol
Four rapid tests for the serologic diagnosis of leptospirosis were evaluated, and the
performance of each was compared with that of the current standard, the microscopic …

Detection of pathogenic leptospires by real-time quantitative PCR

PN Levett, RE Morey, RL Galloway… - Journal of Medical …, 2005 - microbiologyresearch.org
Definitive diagnosis of leptospirosis has traditionally depended upon the isolation of
leptospires from clinical specimens or the demonstration of seroconversion in paired acute …

Two methods for rapid serological diagnosis of acute leptospirosis

PN Levett, SL Branch, CU Whittington… - Clinical Diagnostic …, 2001 - Am Soc Microbiol
Leptospirosis is a common and underdiagnosed zoonosis. Two rapid assays for serological
diagnosis of acute leptospirosis in diagnostic laboratories, the immunoglobulin M (IgM) …