Interleukin-6 signaling in triple negative breast cancer cells elicits the annexin A1/formyl peptide receptor 1 axis and affects the tumor microenvironment
L Vecchi, STS Mota, MAP Zóia, IC Martins… - Cells, 2022 - mdpi.com
Annexin A1 (AnxA1) is a pleiotropic protein that exerts essential roles in breast cancer (BC)
growth and aggressiveness. In our previous work, we described the autocrine signaling of …
growth and aggressiveness. In our previous work, we described the autocrine signaling of …
[HTML][HTML] Inhibition of the AnxA1/FPR1 autocrine axis reduces MDA-MB-231 breast cancer cell growth and aggressiveness in vitro and in vivo
L Vecchi, MAP Zóia, TG Santos… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Breast Cancer (BC) is a highly heterogeneous disease whose most aggressive behavior is
displayed by triple-negative breast cancer (TNBC), which lacks an efficient targeted therapy …
displayed by triple-negative breast cancer (TNBC), which lacks an efficient targeted therapy …
Downregulation of annexin A3 inhibits tumor metastasis and decreases drug resistance in breast cancer
Abstract Annexin A3 (ANXA3) is dysregulated and plays an important role in various
cancers. However, the role of ANXA3 in breast cancer is still unclear. Here, we observed that …
cancers. However, the role of ANXA3 in breast cancer is still unclear. Here, we observed that …
[HTML][HTML] Anxa2 binds to STAT3 and promotes epithelial to mesenchymal transition in breast cancer cells
T Wang, J Yuan, J Zhang, R Tian, W Ji, Y Zhou… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Overexpression of annexin A2 (Anxa2) is correlated with invasion and metastasis in breast
cancer cells. In this study, breast cancer patients with upregulated Anxa2 exhibited poor …
cancer cells. In this study, breast cancer patients with upregulated Anxa2 exhibited poor …
Annexin‐1 signals mitogen‐stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2
T Khau, SY Langenbach, M Schuliga… - The FASEB …, 2011 - Wiley Online Library
The role of the calcium‐and phospho‐lipid‐binding protein annexin I (ANXA1) in cell cycle
regulation has been investigated in estrogen receptor (ER)‐positive MCF‐7 and ER …
regulation has been investigated in estrogen receptor (ER)‐positive MCF‐7 and ER …
Annexin A1 in inflammation and breast cancer: a new axis in the tumor microenvironment
LA Moraes, PB Ampomah, LHK Lim - Cell adhesion & migration, 2018 - Taylor & Francis
Targeting inflammation in cancer has shown promise to improve and complement current
therapies. The tumor microenvironment plays an important role in cancer growth and …
therapies. The tumor microenvironment plays an important role in cancer growth and …
Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment
LA Moraes, S Kar, SL Foo, T Gu, YQ Toh… - Scientific reports, 2017 - nature.com
Macrophages are potent immune cells with well-established roles in the response to stress,
injury, infection and inflammation. The classically activated macrophages (M1) are induced …
injury, infection and inflammation. The classically activated macrophages (M1) are induced …
Upregulated Annexin A1 promotes cellular invasion in triple-negative breast cancer
M Okano, K Kumamoto, M Saito… - Oncology …, 2015 - spandidos-publications.com
Abstract Annexin A1 (ANXA1) is a calcium-dependent phospholipid-linked protein, involved
in anti-inflammatory effects, regulation of cellular differentiation, proliferation and apoptosis …
in anti-inflammatory effects, regulation of cellular differentiation, proliferation and apoptosis …
ANXA4 activates JAK-STAT3 signaling by interacting with ANXA1 in basal-like breast cancer
L Li, R Zhang, Y Liu, G Zhang - DNA and Cell Biology, 2020 - liebertpub.com
Annexin A4 (encoded by the ANXA4 gene) is a calcium ion (Ca2+)-and phospholipid-
binding protein of the Annexin family. In this study, we checked the expression profile of …
binding protein of the Annexin family. In this study, we checked the expression profile of …
Annexin A1 localization and its relevance to cancer
Z Boudhraa, B Bouchon, C Viallard, M D'Incan… - Clinical …, 2016 - portlandpress.com
Annexin A1 (ANXA1) is a Ca2+-regulated phospholipid-binding protein involved in various
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …
cell processes. ANXA1 was initially widely studied in inflammation resolution, but its …
相关搜索
- tumor microenvironment interleukin 6
- tumor microenvironment breast cancer
- annexin a1 tumour microenvironment
- downregulation of annexin breast cancer
- tumor metastasis downregulation of annexin
- annexin a1 macrophage polarization
- cellular invasion breast cancer
- drug resistance breast cancer
- tumor metastasis breast cancer