IgA nephropathy: current understanding and perspectives on pathogenesis and targeted treatment

Y Du, T Cheng, C Liu, T Zhu, C Guo, S Li, X Rao, J Li - Diagnostics, 2023 - mdpi.com
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide, with varied clinical and histopathological features between individuals …

[HTML][HTML] New insights into the pathogenesis and treatment strategies in IgA nephropathy

K Scionti, K Molyneux, H Selvaskandan, J Barratt… - Glomerular …, 2022 - karger.com
Background: Immunoglobulin A nephropathy (IgAN) is the most common form of primary
glomerulonephritis worldwide. It is defined by mesangial IgA deposition, with consequent …

IgA nephropathy: core curriculum 2021

P Pattrapornpisut, C Avila-Casado, HN Reich - American Journal of Kidney …, 2021 - Elsevier
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerular disease
worldwide. The diagnostic histologic hallmark is dominant or codominant IgA staining on …

IgA nephropathy: a perspective for 2021

J Floege, J Barratt - Seminars in Immunopathology, 2021 - Springer
Immunoglobulin A nephropathy (IgAN) is the commonest primary glomerular disease
worldwide and responsible for a significant proportion of the global end-stage kidney …

[HTML][HTML] Is complement the main accomplice in IgA nephropathy? From initial observations to potential complement-targeted therapies

MB Le Stang, PJ Gleeson, MR Daha, RC Monteiro… - Molecular …, 2021 - Elsevier
Abstract IgA Nephropathy (IgAN) is the main cause of primary glomerulonephritis, globally.
This disease is associated with a wide range of clinical presentations, variable prognosis …

New treatment strategies for IgA nephropathy: targeting plasma cells as the main source of pathogenic antibodies

D Maixnerova, D El Mehdi, DV Rizk, H Zhang… - Journal of Clinical …, 2022 - mdpi.com
Immunoglobulin A nephropathy (IgAN) is a rare autoimmune disorder and the leading cause
of biopsy-reported glomerulonephritis (GN) worldwide. Disease progression is driven by the …

IgA nephropathy: an interesting autoimmune kidney disease

A Rajasekaran, BA Julian, DV Rizk - The American journal of the medical …, 2021 - Elsevier
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide. It is a leading cause of chronic kidney disease and progresses to end-stage …

Primary IgA nephropathy: current challenges and future prospects

RS Penfold, M Prendecki, S McAdoo… - International journal of …, 2018 - Taylor & Francis
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide,
exhibiting a variable clinical and pathological course and significantly contributing to the …

A personalized update on IgA nephropathy: a new vision and new future challenges

E Gutiérrez, F Carvaca-Fontán, L Luzardo, E Morales… - Nephron, 2020 - karger.com
IgA nephropathy (IgAN) is the most common primary glomerulonephritis in the world among
patients undergoing renal biopsy. Approximately 30% of patients with IgAN develop end …

The role of immune modulation in pathogenesis of IgA nephropathy

S Chang, XK Li - Frontiers in Medicine, 2020 - frontiersin.org
IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis worldwide, with
diverse clinical manifestations characterized by recurrent gross hematuria or microscopic …