An Insight into the Role of GLIS1 in Embryonic Development, iPSC Generation, and Cancer

KR Ronima, C Dey, RP Thummer - 2023 - Springer
The curiosity to discover transcription factors to reprogram somatic cells to induced
pluripotent stem cells (iPSCs) resulted in the identification of a reprogramming factor, Gli …

[HTML][HTML] Glis family proteins are differentially implicated in the cellular reprogramming of human somatic cells

SY Lee, HB Noh, HT Kim, KI Lee, DY Hwang - Oncotarget, 2017 - ncbi.nlm.nih.gov
The ground-breaking discovery of the reprogramming of somatic cells into pluripotent cells,
termed induced pluripotent stem cells (iPSCs), was accomplished by delivering 4 …

[HTML][HTML] GLIS1-3: emerging roles in reprogramming, stem and progenitor cell differentiation and maintenance

DW Scoville, HS Kang, AM Jetten - Stem cell investigation, 2017 - ncbi.nlm.nih.gov
Recent studies have provided evidence for a regulatory role of GLI-similar (GLIS)
transcription factors in reprogramming, maintenance and differentiation of several stem and …

Identification of Optimal Expression Parameters and Purification of a Codon-Optimized Human GLIS1 Transcription Factor from Escherichia coli

C Dey, V Venkatesan, RP Thummer - Molecular Biotechnology, 2022 - Springer
GLIS1 has multiple roles in embryonic development and in deriving induced pluripotent
stem cells by aiding signaling pathways and chromatin assembly. An inexpensive and …

Evolutionary History of GLIS Genes Illuminates Their Roles in Cell Reprograming and Ciliogenesis

Y Yasuoka, M Matsumoto, K Yagi… - Molecular biology and …, 2020 - academic.oup.com
The GLIS family transcription factors, GLIS1 and GLIS3, potentiate generation of induced
pluripotent stem cells (iPSCs). In contrast, another GLIS family member, GLIS2, suppresses …

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

M Maekawa, K Yamaguchi, T Nakamura, R Shibukawa… - Nature, 2011 - nature.com
Induced pluripotent stem cells (iPSCs) are generated from somatic cells by the transgenic
expression of three transcription factors collectively called OSK: Oct3/4 (also called Pou5f1) …

[PDF][PDF] Glis1, a unique pro-reprogramming factor, may facilitate clinical applications of iPSC technology

M Maekawa, S Yamanaka - Cell Cycle, 2011 - Taylor & Francis
Glis1, a unique pro-reprogramming factor, may facilitate clinical applications of iPSC
technology Page 1 www.landesbioscience.com Cell Cycle 3613 Cell Cycle 10:21, 3613-3614; …

Effects of downregulating GLIS1 transcript on preimplantation development and gene expression of bovine embryos

K Takahashi, N Sakurai, N Emura… - … of Reproduction and …, 2015 - jstage.jst.go.jp
Krüppel-like protein Gli-similar 1 (GLIS1) is known as a direct reprogramming factor for the
generation of induced pluripotent stem cells. The objective of this study was to investigate …

GLIS1–3 transcription factors: critical roles in the regulation of multiple physiological processes and diseases

AM Jetten - Cellular and molecular life sciences, 2018 - Springer
Krüppel-like zinc finger proteins form one of the largest families of transcription factors. They
function as key regulators of embryonic development and a wide range of other …

[HTML][HTML] GLIS1-3: links to primary cilium, reprogramming, stem cell renewal, and disease

AM Jetten, DW Scoville, HS Kang - Cells, 2022 - mdpi.com
The GLI-Similar 1-3 (GLIS1-3) genes, in addition to encoding GLIS1-3 Krüppel-like zinc
finger transcription factors, also generate circular GLIS (circGLIS) RNAs. GLIS1-3 regulate …