Stereotactic ablative radiotherapy versus standard of care palliative treatment in patients with oligometastatic cancers (SABR-COMET): a randomised, phase 2, open …

DA Palma, R Olson, S Harrow, S Gaede, AV Louie… - The Lancet, 2019 - thelancet.com
Background The oligometastatic paradigm suggests that some patients with a limited
number of metastases might be cured if all lesions are eradicated. Evidence from …

Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial

DA Palma, R Olson, S Harrow, S Gaede… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE The oligometastatic paradigm hypothesizes that patients with a limited number of
metastases may achieve long-term disease control, or even cure, if all sites of disease can …

Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial

R Olson, L Mathews, M Liu, D Schellenberg, B Mou… - BMC cancer, 2020 - Springer
Background A recent randomized phase II trial evaluated stereotactic ablative radiotherapy
(SABR) in a group of patients with a small burden of oligometastatic disease (mostly with 1 …

Stereotactic ablative radiotherapy for comprehensive treatment of oligometastatic tumors (SABR-COMET): study protocol for a randomized phase II trial

DA Palma, CJA Haasbeek, GB Rodrigues, M Dahele… - BMC cancer, 2012 - Springer
Background Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment
option for patients with oligometastatic disease. SABR delivers precise, high-dose …

Stereotactic ablative radiation therapy for the comprehensive treatment of oligometastatic tumors (SABR-COMET): results of a randomized trial

DA Palma, RA Olson, S Harrow, S Gaede… - International Journal of …, 2018 - redjournal.org
Results Between February 2012 and August 2016, 99 patients were randomized (33 in Arm
1, 66 in Arm 2) at centers in Canada, Scotland, the Netherlands, and Australia. Median age …

Stereotactic ablative radiotherapy for the comprehensive treatment of 4–10 oligometastatic tumors (SABR-COMET-10): study protocol for a randomized phase III trial

DA Palma, R Olson, S Harrow, RJM Correa… - BMC cancer, 2019 - Springer
Background Stereotactic ablative radiotherapy (SABR) has emerged as a new treatment
option for patients with oligometastatic disease. SABR delivers precise, high-dose …

Safety and survival rates associated with ablative stereotactic radiotherapy for patients with oligometastatic cancer: a systematic review and meta-analysis

EJ Lehrer, R Singh, M Wang, VM Chinchilli… - JAMA …, 2021 - jamanetwork.com
Importance The oligometastatic paradigm postulates that patients with a limited number of
metastases can be treated with ablative local therapy to each site of disease with curative …

Stereotactic ablative body radiotherapy in patients with oligometastatic cancers: a prospective, registry-based, single-arm, observational, evaluation study

A Chalkidou, T Macmillan, MT Grzeda… - The lancet …, 2021 - thelancet.com
Background Stereotactic ablative body radiotherapy (SABR) is increasingly being used to
treat oligometastatic cancers, but high-level evidence to provide a basis for policy making is …

Stereotactic radiation for the comprehensive treatment of oligometastases (SABR-COMET): extended long-term outcomes

S Harrow, DA Palma, R Olson, S Gaede… - International Journal of …, 2022 - Elsevier
Purpose Long-term randomized data assessing the effect of ablative therapies in patients
with oligometastases are lacking. The Stereotactic Ablative Radiotherapy for the …

A review of ongoing trials of stereotactic ablative radiotherapy for oligometastatic cancers: Where will the evidence lead?

F Al-Shafa, AJ Arifin, GB Rodrigues, DA Palma… - Frontiers in …, 2019 - frontiersin.org
Purpose: The oligometastatic state is a proposed entity between localized cancer and widely
metastatic disease, comprising an intermediate subset of metastatic cancer patients. Most …