Understanding and treating trauma and violence-related pathologies in South African townships: Emergence and modifiability of epigenetic and neural memories of …

KR Xulu - 2018 - scholar.sun.ac.za
Abstract ENGLISH SUMMARY: Prolonged exposure to traumatic stress results in sustained
activation of biological responses, which affect shared similar pathways, leading to …

DNA methylation and psychotherapy response in trauma-exposed men with appetitive aggression

KR Xulu, JS Womersley, J Sommer, M Hinsberger… - Psychiatry …, 2021 - Elsevier
Exposure to violence can lead to appetitive aggression (AA), the positive feeling and
fascination associated with violence, and posttraumatic stress disorder (PTSD) …

Sequel of war: Investigating appetitive aggression, violence perpetration, PTSD symptoms and treatment effects using psychological and epigenetic variables of the …

AC Rukundo-Zeller - 2022 - kops.uni-konstanz.de
Aggression and traumatic experiences are common in individuals affected by war. Persons
who are actively involved in organised violence such as combatants or soldiers have …

Associations between telomere length and symptoms of posttraumatic stress disorder and appetitive aggression in trauma-exposed men

JS Womersley, KR Xulu, J Sommer, M Hinsberger… - Neuroscience …, 2022 - Elsevier
Exposure to community violence is common in South Africa and negatively impacts on
biopsychosocial health. Posttraumatic stress disorder (PTSD) is characterised by symptoms …

The risk of posttraumatic stress disorder after trauma depends on traumatic load and the catechol-O-methyltransferase Val158Met polymorphism

IT Kolassa, S Kolassa, V Ertl, A Papassotiropoulos… - Biological …, 2010 - Elsevier
BACKGROUND: The risk for posttraumatic stress disorder (PTSD) depends on the number
of traumatic event types experienced in a dose–response relationship, but genetic factors …

Genome-wide differentially methylated genes associated with post-traumatic stress disorder in female rape survivors

J Nöthling, S Seedat, N Abrahams… - South African Journal of …, 2018 - scielo.org.za
ABSTRACT INTRODUCTION: Alterations to the epigenome in response to psychological
trauma have been reported as a mechanism mediating gene and environmental interaction …

Genome-wide differentially methylated genes associated with post-traumatic stress disorder in female rape survivors

J Nothling, S Seedat, N Abrahams… - South African Journal of …, 2018 - go.gale.com
Introduction: Alterations to the epigenome in response to psychological trauma have been
reported as a mechanism mediating gene and environmental interaction. Differentially …

DNA methylation changes following narrative exposure therapy in a randomized controlled trial with female former child soldiers

S Carleial, D Nätt, E Unternährer, T Elbert, K Robjant… - Scientific reports, 2021 - nature.com
The aftermath of traumatization lives on in the neural and epigenetic traces creating a
momentum of affliction in the psychological and social realm. Can psychotherapy reorganise …

Methylation Quantitative Trait Loci Associated with PTSD in a South African Population

M Du Plessis - 2021 - scholar.sun.ac.za
Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder characterised by
symptoms of intrusive thoughts, avoidance behaviours, hyper-arousal and negative …

[HTML][HTML] The interplay between trauma, substance abuse and appetitive aggression and its relation to criminal activity among high-risk males in South Africa

J Sommer, M Hinsberger, T Elbert, L Holtzhausen… - Addictive …, 2017 - Elsevier
Background In persistently unsafe environments, the cumulative exposure to violence
predicts not only the development of posttraumatic stress disorder (PTSD), but also of …