Hotter is better is a hypothesis of thermal adaptation that posits that the rate-depressing
effects of low temperature on biochemical reactions cannot be overcome by physiological …

Two major goals of laboratory evolution experiments are to integrate from genotype to
phenotype to fitness, and to understand the genetic basis of adaptation in natural …

Diverse biochemical and physiological adaptations enable different species of ectotherms to
survive and reproduce in very different temperature regimes, but whether these adaptations …

Despite decades of research on the evolution of thermal physiology, at least one
fundamental issue remains unresolved: whether the maximal performance of a genotype …

The initial rise of fitness that occurs with increasing temperature is attributed to Arrhenius
kinetics, in which rates of reaction increase exponentially with increasing temperature …

Models of thermal adaptation assume that warm-adapted and cold-adapted organisms can
achieve the same fitness, yet recent comparative studies suggest that warm-adapted …

Resistance to predation, herbivory, or disease often comes at a cost such that resistant
genotypes are competitively inferior to their sensitive counterparts in the absence of …

Optimality models assume that phenotypes evolve by natural selection largely
independently of underlying genetic mechanisms. This neglect of genetic mechanisms is …

We used experimental evolution to test directly the important and commonplace evolutionary
hypothesis that adaptation, increased fitness within the selective environment, is …

For more than a century, biologists have known that body temperature strongly affects the
capacities and rates of organisms and thus is a key determinant of organismal performance …