Tissue regeneration following injury from disease or medical treatment still represents a
challenge in regeneration medicine. Prostaglandin E2 (PGE2), which involves diverse …

INTRODUCTION Agents that promote tissue regeneration could be beneficial in a variety of
clinical settings, such as stimulating recovery of the hematopoietic system after bone marrow …

Prostaglandin E2 (PGE2) is the most abundant eicosanoid and a very potent lipid mediator.
PGE2 is produced predominantly from arachidonic acid by its tightly regulated …

Wound healing is regulated by a complex series of events and overlapping phases. A
delicate balance of cytokines and mediators in tissue repair is required for optimal therapy in …

Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Utility is the price of its perfection. PGE2 is a founding member of the PGs, a class of
mediators that belongs to the still growing family of bioactive autacoids known as the …

Prostaglandin E2 (PGE2) and prostacyclin are lipid mediators produced by cyclooxygenase
and implicated in the regulation of vascular function, wound repair, inflammatory processes …

Neutrophils are the first immune cells recruited to a site of injury or infection, where they
perform many functions. Having completed their role, neutrophils must be removed from the …

Prostaglandins (PG) are the product of a cascade of enzymes such as cyclooxygenases and
PG synthases. Among PG, PGE 2 is produced by 3 isoforms of PGE synthase (PGES) and …

Rationale: Vascular smooth muscle cell (VSMC) migration and proliferation are the
hallmarks of restenosis pathogenesis after angioplasty. Cyclooxygenase (COX)-derived …