Background Idiopathic pulmonary fibrosis (IPF) has high mortality worldwide. The CD247
molecule (CD247, as known as T-cell surface glycoprotein CD3 zeta chain) has been …

Background M2-like/repair macrophages are thought to contribute to fibrotic process of
idiopathic pulmonary fibrosis (IPF). We analyzed the association between pulmonary …

Background Although the etiology of idiopathic pulmonary fibrosis (IPF) remains perplexing,
adaptive immune activation is evident among many afflicted patients. Repeated cycles of …

Background Idiopathic pulmonary fibrosis (IPF) is one of interstitial lung diseases (ILDs) with
poor prognosis. S100 calcium binding protein A12 (S100A12) has been reported as a …

Circulating monocytes have pathogenic relevance in idiopathic pulmonary fibrosis (IPF).
Here, we determined whether the cell surface levels of two markers, pro-inflammatory …

(1) The role of the immune response in the pathogenesis of idiopathic pulmonary fibrosis
(IPF) remains controversial. We hypothesized that peripheral blood immune phenotypes will …

Idiopathic pulmonary fibrosis (IPF) is characterized by progressive deposition of extracellular
matrix, worsening dyspnea, and eventual mortality. Pathogenesis of IPF is poorly …

Background CD248 or Endosialin is a transmembrane molecule expressed in stromal cells
binding to extracellular matrix (ECM) components. It has been previously implicated in …

Background The potential pathogenic mechanism of idiopathic pulmonary fibrosis is widely
recognized to involve immune dysregulation. However, the current pool of studies has yet to …

Rationale: Changes in peripheral blood cell populations have been observed but not
detailed at single-cell resolution in idiopathic pulmonary fibrosis (IPF). Objectives: To …