Immunothrombosis: molecular aspects and new therapeutic perspectives
M Marcos-Jubilar, R Lecumberri… - Journal of Clinical …, 2023 - mdpi.com
Thromboinflammation or immunothrombosis is a concept that explains the existing link
between coagulation and inflammatory response present in many situations, such as sepsis …
between coagulation and inflammatory response present in many situations, such as sepsis …
Interplay between inflammation and thrombosis in cardiovascular pathology
K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …
death worldwide, making it a major health-care challenge. Platelets and the coagulation …
Thrombosis as an intravascular effector of innate immunity
B Engelmann, S Massberg - Nature Reviews Immunology, 2013 - nature.com
Thrombosis is the most frequent cause of mortality worldwide and is closely linked to
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …
haemostasis, which is the biological mechanism that stops bleeding after the injury of blood …
Innate immune signaling and immunothrombosis: New insights and therapeutic opportunities
TAJ Ryan, LAJ O'Neill - European Journal of Immunology, 2022 - Wiley Online Library
Activation of the coagulation cascade is a critical, evolutionarily conserved mechanism that
maintains hemostasis by rapidly forming blood clots in response to blood‐borne infections …
maintains hemostasis by rapidly forming blood clots in response to blood‐borne infections …
Pathophysiological mechanisms of thrombosis in acute and long COVID-19
H Jing, X Wu, M Xiang, L Liu, VA Novakovic… - Frontiers in …, 2022 - frontiersin.org
COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …
Mechanisms of immunothrombosis in COVID-19
I Portier, RA Campbell, F Denorme - Current opinion in …, 2021 - journals.lww.com
Mechanisms of immunothrombosis in COVID-19 : Current Opinion in Hematology
Mechanisms of immunothrombosis in COVID-19 : Current Opinion in Hematology Log in or …
Mechanisms of immunothrombosis in COVID-19 : Current Opinion in Hematology Log in or …
Dysregulated haemostasis in thrombo-inflammatory disease
Inflammatory disease is often associated with an increased incidence of venous
thromboembolism in affected patients, although in most instances, the mechanistic basis for …
thromboembolism in affected patients, although in most instances, the mechanistic basis for …
Immunothrombosis and the role of platelets in venous thromboembolic diseases
M Heestermans, G Poenou, AC Duchez… - International Journal of …, 2022 - mdpi.com
Venous thromboembolism (VTE) is the third leading cardiovascular cause of death and is
conventionally treated with anticoagulants that directly antagonize coagulation. However …
conventionally treated with anticoagulants that directly antagonize coagulation. However …
COVID‐19 and immunothrombosis: emerging understanding and clinical management
RJ Shaw, C Bradbury, ST Abrams… - British journal of …, 2021 - Wiley Online Library
The COVID‐19 pandemic has been the most significant health crisis in recent global history.
Early studies from Wuhan highlighted COVID‐19‐associated coagulopathy and a significant …
Early studies from Wuhan highlighted COVID‐19‐associated coagulopathy and a significant …
COVID-19 and immunothrombosis: Pathophysiology and therapeutic implications
MS Lim, S Mcrae - Critical Reviews in Oncology/Hematology, 2021 - Elsevier
The coagulopathy of COVID-19 is characterised by significantly elevated D Dimer and
fibrinogen, mild thrombocytopenia and a mildly prolonged PT/APTT. A high incidence of …
fibrinogen, mild thrombocytopenia and a mildly prolonged PT/APTT. A high incidence of …